(R)-1-Boc-3-hydroxypiperidine
(R)-1-Boc-3-hydroxypiperidine (CAS: 143900-43-0, C10H19NO3) is a chiral building block essential for asymmetric synthesis and complex chemical manufacturing. This piperidine derivative, with a molecular weight of 201.26 g/mol, serves as a valuable intermediate in the development of novel pharmaceutical agents and other fine chemicals requiring precise stereochemistry. Its protected hydroxyl group and chiral center make it a versatile reagent in multi-step organic synthesis.
- IUPAC
- (R)-tert-Butyl 3-hydroxypiperidine-1-carboxylate
Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) where stereochemical control is critical. Its structure is incorporated into various drug candidates for diverse therapeutic areas.
Chiral Building Block
Serves as a key component in asymmetric synthesis, enabling the construction of complex chiral molecules with high enantiomeric purity. Useful in developing novel organic compounds.
Organic Synthesis Reagent
Employed in research and development laboratories for constructing heterocyclic compounds and functionalised piperidine rings. Facilitates the creation of specialised chemical entities.
| Molecular weight | 201.26 |
|---|---|
| Empirical formula | C10H19NO3 |
| Assay | 95% |
| Optical activity | [α]/D −22±3°, c = 5 in methanol |
| Melting point | 43-50 °C |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Flash point | 104 °C / 219.2 °F |
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-37/38-41 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-1-Boc-3-hydroxypiperidine used for?
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(R)-1-Boc-3-hydroxypiperidine is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the development of pharmaceutical agents and other fine chemicals.
What are the CAS number and formula for (R)-1-Boc-3-hydroxypiperidine?
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The CAS number is 143900-43-0 and the empirical formula is C10H19NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-1-Boc-3-hydroxypiperidine with an assay of 95%. This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, EP, or any other pharmacopoeial grade.
How should (R)-1-Boc-3-hydroxypiperidine be handled?
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This compound is classified as Dangerous. It is harmful if swallowed, causes skin irritation, causes serious eye damage, and may cause respiratory irritation. Handle with appropriate personal protective equipment including eyeshields, face shields, gloves, and a P2 respirator cartridge. Ensure adequate ventilation.
Is (R)-1-Boc-3-hydroxypiperidine a controlled substance?
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The provided data does not indicate that (R)-1-Boc-3-hydroxypiperidine is a controlled substance.
How is (R)-1-Boc-3-hydroxypiperidine packed and shipped?
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(R)-1-Boc-3-hydroxypiperidine is shipped as UN 2811, Class 6.1, Packing Group III. Specific packaging details are available upon request.
How can I request a sample or quote?
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Please contact our sales team directly through our website or by phone to request a sample or a detailed quotation for (R)-1-Boc-3-hydroxypiperidine.
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