(R)-1-Boc-4-hydroxy-2-pyrrolidinone
(R)-1-Boc-4-hydroxy-2-pyrrolidinone (CAS: 320343-60-0; C9H15NO4) is a chiral heterocyclic compound with a molecular weight of 201.22 g/mol. This Boc-protected pyrrolidinone derivative is a valuable building block in organic synthesis. It is primarily utilised in asymmetric synthesis and the construction of complex chiral molecules, finding applications in the development of pharmaceuticals and other fine chemicals.
- IUPAC
- tert-Butyl (R)-4-hydroxy-2-oxopyrrolidine-1-carboxylate

Chiral Building Block in Organic Synthesis
Serves as a key intermediate in the synthesis of enantiomerically pure compounds. Its defined stereochemistry allows for the controlled introduction of chirality in target molecules.
Pharmaceutical Intermediate Development
Utilised in the research and development of novel pharmaceutical agents. The pyrrolidinone scaffold is present in various biologically active molecules.
Asymmetric Synthesis Applications
Enables stereoselective transformations, making it valuable for creating complex molecular architectures with high enantiomeric purity.
| Molecular weight | 201.22 |
|---|---|
| Empirical formula | C9H15NO4 |
| Assay | 97% |
| Optical activity | [α]22/D -28.0°, c = 0.5% in chloroform |
| Melting point | 136-141 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38-52/53 |
| Safety statements (S) | 26-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-1-Boc-4-hydroxy-2-pyrrolidinone used for?
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(R)-1-Boc-4-hydroxy-2-pyrrolidinone is primarily used as a chiral building block in organic synthesis, particularly for asymmetric synthesis and the development of pharmaceutical intermediates.
What is the CAS number and molecular formula for (R)-1-Boc-4-hydroxy-2-pyrrolidinone?
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The CAS number is 320343-60-0 and the molecular formula is C9H15NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-1-Boc-4-hydroxy-2-pyrrolidinone with a minimum assay of 97%. This product is not classified as USP, BP, or EP grade.
How should (R)-1-Boc-4-hydroxy-2-pyrrolidinone be handled?
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Handle (R)-1-Boc-4-hydroxy-2-pyrrolidinone with appropriate personal protective equipment in a well-ventilated area. It is a Warning substance (GHS07) with hazards H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Avoid inhalation, skin and eye contact. Ensure proper disposal according to regulations (WGK 3).
How is (R)-1-Boc-4-hydroxy-2-pyrrolidinone packed and shipped?
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(R)-1-Boc-4-hydroxy-2-pyrrolidinone is carefully packed to ensure product integrity during transit and is exported globally by Tech Serve Solutions.
How can I request a sample or quote for (R)-1-Boc-4-hydroxy-2-pyrrolidinone?
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Please contact our sales team via the website or direct email to request a sample or a quotation for (R)-1-Boc-4-hydroxy-2-pyrrolidinone.
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