(R)-1-Boc-3-methylpiperazine
(R)-1-Boc-3-methylpiperazine (CAS 163765-44-4, C10H20N2O2) is a chiral building block with a molecular weight of 200.28. This N-protected piperazine derivative is valuable in asymmetric synthesis and general chemical synthesis, particularly for constructing complex heterocyclic molecules. Its defined stereochemistry makes it a key intermediate in the development of pharmaceuticals and other fine chemicals requiring precise molecular architecture.
- IUPAC
- tert-Butyl (R)-3-methyl-1-piperazinecarboxylate

Asymmetric Synthesis
Serves as a chiral intermediate for enantioselective synthesis, enabling the creation of stereochemically pure target molecules.
Pharmaceutical Intermediates
Utilised in the synthetic routes for developing new drug candidates and active pharmaceutical ingredients where specific chirality is critical.
Heterocyclic Chemistry
A versatile building block for the synthesis of complex heterocyclic compounds, including substituted piperazine scaffolds.
Chemical Synthesis Research
Employed in research laboratories for exploring novel synthetic methodologies and creating complex organic molecules.
| Molecular weight | 200.28 |
|---|---|
| Empirical formula | C10H20N2O2 |
| Assay | 97% |


Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 106 °C / 222.8 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-1-Boc-3-methylpiperazine used for?
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(R)-1-Boc-3-methylpiperazine is primarily used as a chiral building block in asymmetric synthesis and for the development of pharmaceutical intermediates and other complex heterocyclic compounds.
What are the CAS number and formula for (R)-1-Boc-3-methylpiperazine?
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The CAS number for (R)-1-Boc-3-methylpiperazine is 163765-44-4, and its empirical formula is C10H20N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-1-Boc-3-methylpiperazine with a minimum purity of 97%. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should (R)-1-Boc-3-methylpiperazine be handled safely?
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Handle (R)-1-Boc-3-methylpiperazine with appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust. It is classified as a Danger with hazards including skin irritation, serious eye damage, and respiratory irritation (H315, H318, H335).
How is this chemical exported and shipped?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. We adhere to all relevant regulations for the safe packaging, shipping, and export of (R)-1-Boc-3-methylpiperazine.
How can I request a quote or sample for (R)-1-Boc-3-methylpiperazine?
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To request a quote or sample, please contact our sales team through the TSS website or by phone, providing the product name and CAS number (163765-44-4).
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