Tris(trimethylsilyl)silane
Tris(trimethylsilyl)silane (CAS 1873-77-4) is an organosilicon compound with the formula [(CH3)3Si]3SiH and a molecular weight of 248.66 g/mol. This chemical is primarily utilised as a versatile reducing agent and as a precursor for introducing the bulky tris(trimethylsilyl)silyl (TTMSS) group in organic synthesis. Its unique structure lends itself to applications in hydrosilylations, radical reactions, and the formation of carbon-carbon bonds, making it valuable in advanced chemical research and development.
- IUPAC
- 1,1,1,3,3,3-Hexamethyl-2-trimethylsilyl-trisilane,TTMSS
![Tris(trimethylsilyl)silane ([(CH3)3Si]3SiH) — chemical structure, CAS 1873-77-4; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1873-77-4.png&w=3840&q=75)
Reducing Agent
Tris(trimethylsilyl)silane serves as a selective reducing agent for various functional groups, including acid chlorides and carbon-halogen bonds. It is also employed in hydrosilylations of carbonyl compounds, facilitating the formation of new silicon-carbon bonds.
Super Silyl Protecting Groups
The tris(trimethylsilyl)silyl (TTMSS) moiety, introduced using this reagent, functions as a bulky protecting group in organometallic chemistry. This 'super silyl' group is stabilising when complexed with transition metals and main group elements.
Radical and C-C Bond Formation
This silane participates in radical reactions and has found recent utility in the construction of carbon-carbon bonds. Its reactivity profile makes it a useful tool for complex organic synthesis strategies.
| Molecular weight | 248.66 |
|---|---|
| Linear formula | [(CH3)3Si]3SiH |
| Assay | 97% |
| Boiling point | 73 °C/5 mmHg(lit.) |
| Density | 0.806 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.489(lit.) |
| Application | Super Silyl Protecting GroupsUsed in:• Hydrosilylations1• Radical reactions2• Reductions of acid chlorides3• Reductions of carbon-halogen bonds4• Hydrosilations of carbonyls5• Another common application involves the use of the tris(trimethylsilyl)silyl (TTMSS, or super silyl) group when complexed with transition metals and main group elements6,7• More recently, the super silyl group is being utilized in carbon–carbon bond forming reactions8 |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 55 °C / 131 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tris(trimethylsilyl)silane used for?
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Tris(trimethylsilyl)silane is used in organic synthesis as a reducing agent for acid chlorides and carbon-halogen bonds, in hydrosilylations, radical reactions, and for introducing the bulky tris(trimethylsilyl)silyl (TTMSS) protecting group.
What are the CAS number and formula for Tris(trimethylsilyl)silane?
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The CAS number is 1873-77-4 and the linear formula is [(CH3)3Si]3SiH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tris(trimethylsilyl)silane with an assay of 97%. This product is typically supplied for research and laboratory use and is not represented as USP, BP, or EP grade.
How should Tris(trimethylsilyl)silane be handled safely?
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Tris(trimethylsilyl)silane is a flammable liquid and vapour (H226) and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle in a well-ventilated area, away from ignition sources, wearing appropriate personal protective equipment including eyeshields, gloves, and respiratory protection.
How is Tris(trimethylsilyl)silane packed, shipped, and exported?
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Tris(trimethylsilyl)silane is packed and shipped according to international transport regulations for hazardous materials (UN 1993, Class 3, Packing Group III). Tech Serve Solutions exports this chemical globally.
How can I request a sample or quote for Tris(trimethylsilyl)silane?
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To request a sample or a quotation, please contact the Tech Serve Solutions sales team through our website or by calling our office. Please specify the quantity and your delivery location.
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