Tris(trimethylsilyl) phosphate
Tris(trimethylsilyl) phosphate (CAS 10497-05-9) with the formula [(CH3)3SiO]3P(O) and a molecular weight of 314.54 g/mol is a useful organophosphorus compound. Supplied by Tech Serve Solutions with an assay of ≥98%, it serves as a key building block and reagent in chemical synthesis, particularly within organic chemistry and the development of phosphorus-containing materials. Its properties make it valuable for researchers and industrial chemists.
- IUPAC
- Phosphoric acid tris(trimethylsilyl ester)
- Synonyms
- Phosphoric acid tris(trimethylsilyl ester)
![Tris(trimethylsilyl) phosphate ([(CH3)3SiO]3P(O)) — chemical structure, CAS 10497-05-9; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F10497-05-9.png&w=3840&q=75)
Reagent in Organic Synthesis
Tris(trimethylsilyl) phosphate functions as a versatile reagent in various organic transformations. It is employed in the silylation of alcohols and other nucleophiles, facilitating subsequent reactions or protecting functional groups.
Phosphorus Compound Precursor
This compound can serve as a precursor for introducing phosphorus into organic molecules. Its structure allows for controlled incorporation of the phosphate moiety in the synthesis of complex organophosphorus compounds.
Research and Development
Used in laboratory settings for academic and industrial research, Tris(trimethylsilyl) phosphate aids in exploring novel synthetic pathways and developing new materials. Its predictable reactivity makes it a reliable choice for experimental work.
| Molecular weight | 314.54 |
|---|---|
| Linear formula | [(CH3)3SiO]3P(O) |
| Assay | ≥98% |
| Boiling point | 228-229 °C/720 mmHg(lit.) |
| Density | 0.945 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.409(lit.) |
| Melting point | 3-4 °C(lit.) |


Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 13 °C / 55.4 °F |
| Transport (UN / ADR) | UN 1993BF 3 / PGII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tris(trimethylsilyl) phosphate used for?
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Tris(trimethylsilyl) phosphate is used as a reagent in organic synthesis and as a precursor for phosphorus compounds in research and development.
What are the CAS number and formula for Tris(trimethylsilyl) phosphate?
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The CAS number is 10497-05-9 and the chemical formula is [(CH3)3SiO]3P(O).
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tris(trimethylsilyl) phosphate with an assay of ≥98%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
What are the primary safety concerns with Tris(trimethylsilyl) phosphate?
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Tris(trimethylsilyl) phosphate is flammable (H225) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). It requires careful handling with appropriate personal protective equipment.
How is Tris(trimethylsilyl) phosphate packed, shipped, and exported?
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As a global supplier, Tech Serve Solutions ensures proper packaging and adherence to international regulations for the safe shipment and export of Tris(trimethylsilyl) phosphate.
How can I request a sample or quote for Tris(trimethylsilyl) phosphate?
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Please contact our sales team directly through our website or by phone to request a sample or obtain a quotation for Tris(trimethylsilyl) phosphate.
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