(R)-1-Boc-3-pyrrolidinecarboxylic acid
(R)-1-Boc-3-pyrrolidinecarboxylic acid (CAS: 72925-16-7), with the molecular formula C10H17NO4 and a molecular weight of 215.25 g/mol, is a key chiral building block. This compound is primarily utilised in chemical synthesis, particularly for the construction of complex heterocyclic molecules. Its protected amine and carboxylic acid functionalities make it a versatile intermediate in organic chemistry research and development.
- IUPAC
- (R)-1-(tert-Butoxycarbonyl)-3-pyrrolidinecarboxylic acid,N-Boc-L-β-proline
- Synonyms
- (R)-1-(tert-Butoxycarbonyl)-3-pyrrolidinecarboxylic acidN-Boc-L-β-proline
Chiral Intermediate in Organic Synthesis
Serves as a crucial chiral building block for synthesising complex organic molecules, including pharmaceuticals and agrochemicals. Its stereochemistry is valuable for creating enantiomerically pure target compounds.
Pharmaceutical Research and Development
Utilised in the development of novel drug candidates, where the pyrrolidine ring system is a common structural motif in biologically active compounds. The Boc protection allows for selective manipulation of the molecule.
Heterocyclic Chemistry
A valuable reagent for constructing substituted pyrrolidine derivatives and other nitrogen-containing heterocyclic systems. These structures are prevalent in many natural products and synthetic drugs.
| Molecular weight | 215.25 |
|---|---|
| Empirical formula | C10H17NO4 |
| Assay | 97% |
| Optical activity | [α]/D -15.0, c = 0.5% in chloroform |
| Storage temperature | 2-8°C |
| Melting point | 138-143 °C |
Hazard statements
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | N |
| Risk statements (R) | 50 |
| Safety statements (S) | 61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-1-Boc-3-pyrrolidinecarboxylic acid used for?
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This compound is a chiral building block used in organic synthesis, particularly for pharmaceuticals and heterocyclic chemistry.
What are the CAS number and formula for (R)-1-Boc-3-pyrrolidinecarboxylic acid?
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The CAS number is 72925-16-7 and the empirical formula is C10H17NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should (R)-1-Boc-3-pyrrolidinecarboxylic acid be handled and stored?
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This compound is classified as very toxic to aquatic life. It should be handled with care to avoid release into the environment. Store at 2-8°C.
Is this chemical suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.
How can I request a sample or quote?
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Please contact our sales team or use the online enquiry form on our website to request a sample or quote for (R)-1-Boc-3-pyrrolidinecarboxylic acid.
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