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N,N-Dimethylphosphoramic dichloride

CAS 677-43-0(CH3)2NP(O)Cl2Organic Building Blocks

N,N-Dimethylphosphoramic dichloride (CAS: 677-43-0) is a chemical compound with the molecular formula (CH3)2NP(O)Cl2 and a molecular weight of 161.95 g/mol. This organophosphorus halide serves as a valuable reagent and building block in organic synthesis, particularly for introducing the dimethylphosphinoyl group. It is commonly employed in the preparation of various organophosphorus compounds and intermediates within chemical research and development.

IUPAC
DMPADC,Dimethylamidophosphoric dichloride
Synonyms
(CH3)2NP(O)Cl2DMPADCDimethylamidophosphoric dichloride
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N,N-Dimethylphosphoramic dichloride ((CH3)2NP(O)Cl2) — chemical structure, CAS 677-43-0; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksChemical SynthesisOrganic Building BlocksPhosphorus CompoundsPhosphorus Halides
01 /Applications

Organic Synthesis

N,N-Dimethylphosphoramic dichloride acts as a key intermediate and building block in complex organic syntheses. Its reactive nature allows for efficient derivatization in the construction of novel organophosphorus molecules.

Phosphorus Compound Preparation

This compound is instrumental in the synthesis of a wide array of organophosphorus compounds. It facilitates the introduction of specific phosphorus-containing functionalities into target molecules.

Research and Development

Used in laboratory settings for exploring new synthetic pathways and developing novel materials or pharmaceuticals. Its defined reactivity makes it a predictable reagent for chemical transformations.

02 /Properties
Molecular weight161.95
Linear formula(CH3)2NP(O)Cl2
Assay≥98.0% (AT)
Boiling point77-79 °C/11 mmHg(lit.)
Density1.362 g/mL at 20 °C(lit.)
Refractive indexn20/D 1.464
Storage temperature2-8°C
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
Danger

Hazard statements

  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Transport (UN / ADR)UN 3265 8 / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)34-37
Safety statements (S)26-36/37/39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
677-43-0
MDL number
MFCD00013896
Beilstein registry
969956
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is N,N-Dimethylphosphoramic dichloride used for?

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N,N-Dimethylphosphoramic dichloride is primarily used as a building block and reagent in organic synthesis, particularly for preparing other organophosphorus compounds and intermediates.

What is the CAS number and formula for N,N-Dimethylphosphoramic dichloride?

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The CAS number is 677-43-0 and the linear formula is (CH3)2NP(O)Cl2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies N,N-Dimethylphosphoramic dichloride with a purity of ≥98.0% (AT). This is a technical/research grade, and TSS does not represent it as USP, BP, or EP grade.

How should N,N-Dimethylphosphoramic dichloride be handled?

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N,N-Dimethylphosphoramic dichloride is a Danger hazard (H314), causing severe skin burns and eye damage. Handle with extreme care, using full personal protective equipment including face shield, goggles, gloves, and appropriate respiratory protection. Ensure adequate ventilation.

How is N,N-Dimethylphosphoramic dichloride packed and shipped?

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N,N-Dimethylphosphoramic dichloride is classified as UN 3265, 8 / PG III. Shipments adhere to strict regulatory requirements for corrosive materials. TSS is a specialist global supplier and exporter experienced in handling such chemicals.

How can I request a sample or quote for N,N-Dimethylphosphoramic dichloride?

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To request a sample or a quote, please contact the Tech Serve Solutions sales team through our website or by calling us directly. We will be happy to assist you with your inquiry.

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