(R)-(−)-Phenylephrine hydrochloride
(R)-(−)-Phenylephrine hydrochloride (CAS: 61-76-7) is a chemical compound with the linear formula HOC<sub>6</sub>H<sub>4</sub>CH(CH<sub>2</sub>NHCH<sub>3</sub>)OH·HCl and a molecular weight of 203.67 g/mol. This chiral molecule is primarily recognised for its role in asymmetric synthesis and as a bioactive small molecule. It finds applications in various chemical and biological research settings, leveraging its specific stereochemistry for targeted reactions and studies.
- IUPAC
- (R)-(−)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride,(R)-(−)-3-Hydroxy-α-(methylaminomethyl)benzyl alcohol hydrochloride
- Synonyms
- (R)-(−)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride(R)-(−)-3-Hydroxy-α-(methylaminomethyl)benzyl alcohol hydrochloride

Asymmetric Synthesis
(R)-(−)-Phenylephrine hydrochloride serves as a valuable chiral building block in asymmetric synthesis. Its defined stereochemistry allows for the stereoselective construction of complex molecules, crucial in pharmaceutical and fine chemical development.
Bioactive Small Molecule Research
As a bioactive small molecule, this compound is utilised in cell biology and biochemical research. It can be employed to investigate biological pathways or as a reference standard in analytical studies.
Chemical Synthesis Reagent
This compound acts as a versatile reagent in chemical synthesis. Its functional groups and specific chirality make it suitable for incorporation into various synthetic routes, particularly where stereocontrol is paramount.
| Molecular weight | 203.67 |
|---|---|
| Linear formula | HOC6H4CH(CH2NHCH3)OH·HCl |
| Assay | ≥98.0% (CHN) |
| Grade | purum |
| Optical activity | [α]20/D −45±2°, c = 5% in H2O |
| Melting point | 140-145 °C143-145 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-Phenylephrine hydrochloride primarily used for?
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Primarily, (R)-(−)-Phenylephrine hydrochloride is used in asymmetric synthesis and as a bioactive small molecule for research purposes in chemical and cell biology.
What are the CAS number and chemical formula for this compound?
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The CAS number is 61-76-7 and the linear formula is HOC<sub>6</sub>H<sub>4</sub>CH(CH<sub>2</sub>NHCH<sub>3</sub>)OH·HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-Phenylephrine hydrochloride in purum grade with an assay of ≥98.0% (CHN). TSS does not represent this product as USP, BP, or EP grade.
How should (R)-(−)-Phenylephrine hydrochloride be handled safely?
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Handle with care. This compound is a warning hazard, with specific warnings for oral toxicity (H302), skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Use appropriate personal protective equipment including a dust mask (N95), eyeshields, face shields, and gloves. Ensure good ventilation and avoid dust formation.
How is (R)-(−)-Phenylephrine hydrochloride packed, shipped, and exported?
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(R)-(−)-Phenylephrine hydrochloride is carefully packed according to international shipping regulations and exported globally by Tech Serve Solutions to meet diverse research and industrial needs.
How can I request a sample or quote for (R)-(−)-Phenylephrine hydrochloride?
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To request a sample or a quotation, please contact the Tech Serve Solutions sales team through our website or by direct inquiry, providing your specific requirements.
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