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(R)-(−)-Phenylephrine hydrochloride

CAS 61-76-7HOC6H4CH(CH2NHCH3)OH·HClChemical Synthesis

(R)-(−)-Phenylephrine hydrochloride (CAS: 61-76-7) is a chemical compound with the linear formula HOC<sub>6</sub>H<sub>4</sub>CH(CH<sub>2</sub>NHCH<sub>3</sub>)OH·HCl and a molecular weight of 203.67 g/mol. This chiral molecule is primarily recognised for its role in asymmetric synthesis and as a bioactive small molecule. It finds applications in various chemical and biological research settings, leveraging its specific stereochemistry for targeted reactions and studies.

IUPAC
(R)-(−)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride,(R)-(−)-3-Hydroxy-α-(methylaminomethyl)benzyl alcohol hydrochloride
Synonyms
(R)-(−)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride(R)-(−)-3-Hydroxy-α-(methylaminomethyl)benzyl alcohol hydrochloride
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(R)-(−)-Phenylephrine hydrochloride (HOC6H4CH(CH2NHCH3)OH·HCl) — chemical structure, CAS 61-76-7; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisBioactive Small MoleculesCell BiologyChemical SynthesisChiral AuxiliariesEphedrine DerivativesP More...
01 /Applications

Asymmetric Synthesis

(R)-(−)-Phenylephrine hydrochloride serves as a valuable chiral building block in asymmetric synthesis. Its defined stereochemistry allows for the stereoselective construction of complex molecules, crucial in pharmaceutical and fine chemical development.

Bioactive Small Molecule Research

As a bioactive small molecule, this compound is utilised in cell biology and biochemical research. It can be employed to investigate biological pathways or as a reference standard in analytical studies.

Chemical Synthesis Reagent

This compound acts as a versatile reagent in chemical synthesis. Its functional groups and specific chirality make it suitable for incorporation into various synthetic routes, particularly where stereocontrol is paramount.

02 /Properties
Molecular weight203.67
Linear formulaHOC6H4CH(CH2NHCH3)OH·HCl
Assay≥98.0% (CHN)
Gradepurum
Optical activity[α]20/D −45±2°, c = 5% in H2O
Melting point140-145 °C143-145 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Faceshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)22-36/37/38
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
61-76-7
MDL number
MFCD00012605
Beilstein registry
4158948
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (R)-(−)-Phenylephrine hydrochloride primarily used for?

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Primarily, (R)-(−)-Phenylephrine hydrochloride is used in asymmetric synthesis and as a bioactive small molecule for research purposes in chemical and cell biology.

What are the CAS number and chemical formula for this compound?

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The CAS number is 61-76-7 and the linear formula is HOC<sub>6</sub>H<sub>4</sub>CH(CH<sub>2</sub>NHCH<sub>3</sub>)OH·HCl.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (R)-(−)-Phenylephrine hydrochloride in purum grade with an assay of ≥98.0% (CHN). TSS does not represent this product as USP, BP, or EP grade.

How should (R)-(−)-Phenylephrine hydrochloride be handled safely?

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Handle with care. This compound is a warning hazard, with specific warnings for oral toxicity (H302), skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Use appropriate personal protective equipment including a dust mask (N95), eyeshields, face shields, and gloves. Ensure good ventilation and avoid dust formation.

How is (R)-(−)-Phenylephrine hydrochloride packed, shipped, and exported?

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(R)-(−)-Phenylephrine hydrochloride is carefully packed according to international shipping regulations and exported globally by Tech Serve Solutions to meet diverse research and industrial needs.

How can I request a sample or quote for (R)-(−)-Phenylephrine hydrochloride?

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To request a sample or a quotation, please contact the Tech Serve Solutions sales team through our website or by direct inquiry, providing your specific requirements.

Need (R)-(−)-Phenylephrine hydrochloride in a specific grade or volume?