(R)-(−)-N-[1-(1-Naphthyl)ethyl]-3,5-dinitrobenzamide
(R)-(−)-N-[1-(1-Naphthyl)ethyl]-3,5-dinitrobenzamide (CAS: 85922-30-1) is a chiral organic compound with the molecular formula (O2N)2C6H3CONHCH(C10H7)CH3 and a molecular weight of 365.34. This compound serves as a highly effective chiral selector for creating 'brush-type' HPLC stationary phases. Its primary application lies in enantioseparation, enabling the resolution of stereoisomers with high efficiency in chromatographic techniques.
- Synonyms
- (O2N)2C6H3CONHCH(C10H7)CH3
![(R)-(−)-N-[1-(1-Naphthyl)ethyl]-3,5-dinitrobenzamide ((O2N)2C6H3CONHCH(C10H7)CH3) — chemical structure, CAS 85922-30-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F85922-30-1.png&w=3840&q=75)
Chiral Stationary Phase (CSP) for HPLC
This compound is a key component in the synthesis of 'brush-type' chiral stationary phases for High-Performance Liquid Chromatography (HPLC). It enables the efficient separation of enantiomers based on their differential interactions with the chiral selector bonded to the silica matrix.
Enantioseparation
Utilised as a chiral selector, it facilitates the resolution of racemic mixtures into their individual enantiomers. This is critical in pharmaceutical research and quality control where the stereochemistry of a compound can significantly impact its biological activity.
Asymmetric Synthesis
Acts as a valuable chiral building block or reagent in asymmetric synthesis, aiding in the stereoselective creation of complex molecules with defined stereochemistry.
| Molecular weight | 365.34 |
|---|---|
| Linear formula | (O2N)2C6H3CONHCH(C10H7)CH3 |
| Assay | 97% |
| Optical activity | [α]22/D −112°, c = 2 in acetone |
| Application | One of the most successful chiral stationary phases (CSP) for HPLC is the ′brush-type′ phase that contains a silica matrix with covalently bonded chiral groups.This chiral selector is used to make a very efficient ′brush-type′ HPLC stationary phase for enantiomer separation.1 |
| Melting point | 224-226 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-N-[1-(1-Naphthyl)ethyl]-3,5-dinitrobenzamide used for?
+
This compound is primarily used as a chiral selector for creating efficient 'brush-type' HPLC stationary phases, enabling the separation of enantiomers. It also serves as a chiral building block in asymmetric synthesis.
What is the CAS number and formula for this compound?
+
The CAS number is 85922-30-1, and its linear formula is (O2N)2C6H3CONHCH(C10H7)CH3.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this chemical with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should this chemical be handled safely?
+
This compound is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). When handling, wear a dust mask type N95 (US), eyeshields, and gloves. Ensure good ventilation and avoid breathing dust. In case of contact with eyes, rinse cautiously with water for several minutes (P305 + P351 + P338).
Is this chemical controlled or scheduled?
+
The provided data does not indicate that this chemical is a controlled or scheduled substance.
How is this chemical packed, shipped, and exported?
+
This chemical is carefully packed to ensure stability during transit. Tech Serve Solutions, established in 1998, is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a sample or quote?
+
To request a sample or a quote for (R)-(−)-N-[1-(1-Naphthyl)ethyl]-3,5-dinitrobenzamide, please contact our sales team through the TSS website or via the provided contact details.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis