(R)-(−)-N-(3,5-Dinitrobenzoyl)-α-phenylglycine
(R)-(−)-N-(3,5-Dinitrobenzoyl)-α-phenylglycine (CAS 74927-72-3) is a chiral derivatizing reagent with the molecular formula (O₂N)₂C₆H₃CONHCH(C₆H₅)CO₂H and a molecular weight of 345.26 g/mol. This compound is primarily utilised in analytical chemistry for the derivatisation of chiral compounds, particularly amino acids, to facilitate their separation and analysis using techniques such as HPLC. Its structure incorporates a dinitrobenzoyl moiety, enhancing UV detection capabilities.
- IUPAC
- N-(3,5-Dinitrobenzoyl)-D-α-phenylglycine,R-(−)-N-(3,5-Dinitrobenzoyl)phenylglycine
- Synonyms
- (O2N)2C6H3CONHCH(C6H5)CO2HN-(3,5-Dinitrobenzoyl)-D-α-phenylglycineR-(−)-N-(3,5-Dinitrobenzoyl)phenylglycine
Chiral Derivatisation Reagent
This compound serves as a crucial reagent for the derivatisation of chiral molecules, enabling the separation of enantiomers. It is particularly effective for the analysis of amino acids and related compounds.
HPLC Analysis
The dinitrobenzoyl group confers strong UV absorbance, making derivatives of this compound ideal for detection in High-Performance Liquid Chromatography (HPLC) systems. This facilitates sensitive and accurate quantification.
Unnatural Amino Acid Analysis
It is employed in the study and analysis of unnatural amino acids, aiding researchers in understanding their properties and behaviour in various chemical and biological contexts.
Peptide Chemistry
In peptide synthesis and analysis, this reagent can be used to derivatise amino acid residues, assisting in the characterisation and sequencing of peptides.
| Molecular weight | 345.26 |
|---|---|
| Linear formula | (O2N)2C6H3CONHCH(C6H5)CO2H |
| Assay | 99% |
| Optical activity | [α]20/D −102°, c = 0.9 in THF |
| Melting point | 216-217 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-N-(3,5-Dinitrobenzoyl)-α-phenylglycine used for?
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(R)-(−)-N-(3,5-Dinitrobenzoyl)-α-phenylglycine is primarily used as a chiral derivatizing reagent in analytical chemistry, particularly for the separation and analysis of enantiomers via techniques like HPLC, and in the study of unnatural amino acids and peptide chemistry.
What is the CAS number and molecular formula for (R)-(−)-N-(3,5-Dinitrobenzoyl)-α-phenylglycine?
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The CAS number is 74927-72-3 and the linear molecular formula is (O₂N)₂C₆H₃CONHCH(C₆H₅)CO₂H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-N-(3,5-Dinitrobenzoyl)-α-phenylglycine with an assay of 99%. We do not represent this product as USP, BP, or EP grade; it is suitable for research and analytical purposes.
How should (R)-(−)-N-(3,5-Dinitrobenzoyl)-α-phenylglycine be handled?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter due to potential respiratory irritation. Consult the Safety Data Sheet (SDS) for detailed safety information. WGK Germany classification is 3.
How is this chemical packed and shipped?
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Tech Serve Solutions expertly packs and exports fine chemicals globally, adhering to all relevant shipping regulations to ensure safe and timely delivery.
How can I request a quote or sample?
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To request a quote or sample of (R)-(−)-N-(3,5-Dinitrobenzoyl)-α-phenylglycine, please contact our sales team through our website or designated contact channels.
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