(R)-(−)-N-Benzyl-2-phenylglycinol
(R)-(−)-N-Benzyl-2-phenylglycinol (CAS: 14231-57-3) is a chiral amino alcohol with the linear formula C 6 5 CH 2 NHCH(C 6 5 )CH 2 OH and a molecular weight of 227.30 g/mol. This compound serves as a valuable building block in asymmetric synthesis. It is particularly utilised as a starting material for the preparation of optically pure β -substituted amines and the asymmetric synthesis of α -amino phosphonic acids.

Asymmetric Synthesis of α -Amino Phosphonic Acids
This compound is employed as a key reagent in the asymmetric synthesis of α -amino phosphonic acids, enabling the stereoselective formation of these important molecules. Its chiral nature is crucial for controlling the stereochemistry of the products.
Synthesis of Optically Pure β -Substituted Amines
It acts as a starting material for a practical route to optically pure β -substituted amines. This application highlights its utility in generating enantiomerically enriched amine compounds for various chemical applications.
Chiral Building Block
As a chiral amino alcohol derivative, (R)-(−)-N-Benzyl-2-phenylglycinol functions as a versatile chiral building block in complex organic synthesis, facilitating the construction of stereochemically defined molecules.
| Molecular weight | 227.30 |
|---|---|
| Linear formula | C6H5CH2NHCH(C6H5)CH2OH |
| Assay | 98% |
| Boiling point | 87-90 °C(lit.) |
| Optical activity | [α]21/D −80°, c = 0.85 in ethanol |
| Application | Used for the asymmetric synthesis of α-amino phosphonic acids.1 Starting material for a practical route to optically pure β-substituted amines.2 |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-N-Benzyl-2-phenylglycinol used for?
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(R)-(−)-N-Benzyl-2-phenylglycinol is used for the asymmetric synthesis of α -amino phosphonic acids and as a starting material for optically pure β -substituted amines.
What is the CAS number and formula for (R)-(−)-N-Benzyl-2-phenylglycinol?
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The CAS number is 14231-57-3 and the linear formula is C 6 5 CH 2 NHCH(C 6 5 )CH 2 OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-N-Benzyl-2-phenylglycinol with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations when handling (R)-(−)-N-Benzyl-2-phenylglycinol?
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This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area.
How is (R)-(−)-N-Benzyl-2-phenylglycinol packed and shipped?
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Tech Serve Solutions, as a global supplier and exporter, packs and ships chemicals in compliance with international regulations to ensure safe and secure delivery worldwide.
How can I request a sample or quote for (R)-(−)-N-Benzyl-2-phenylglycinol?
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To request a sample or a quote, please contact our sales team through the website or by calling us. Please provide the product name and CAS number (14231-57-3).
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