(R)-(−)-Mandelic acid
(R)-(−)-Mandelic acid (CAS: 611-71-2), a chiral carboxylic acid with the formula C6H5CH(OH)CO2H and a molecular weight of 152.15 g/mol, is a vital building block in asymmetric synthesis. This optically active compound is primarily employed for the chiral resolution of racemic mixtures and as a key intermediate in the synthesis of complex organic molecules and pharmaceuticals. Its specific stereochemistry makes it invaluable for creating enantiomerically pure compounds.
- IUPAC
- (R)-α-Hydroxyphenylacetic acid
- Synonyms
- (R)-Mandelic acid(R)-2-Hydroxy-2-phenylacetic acid(R)-alpha-Hydroxyphenylacetic acid
Chiral Resolution
Utilised as a chiral resolving agent to separate racemic mixtures into their individual enantiomers, a critical step in the production of stereochemically pure active pharmaceutical ingredients.
Asymmetric Synthesis
Serves as a chiral building block, introducing stereochemical control in the synthesis of complex organic molecules and fine chemicals.
Pharmaceutical Intermediates
A key intermediate in the synthesis pathways of various pharmaceutical compounds, contributing to the development of enantiomerically pure drugs.
Organic Synthesis
Employed as a versatile reagent in general organic synthesis for the creation of chiral centres and specific stereoisomers.
| Molecular weight | 152.15 |
|---|---|
| Linear formula | C6H5CH(OH)CO2H |
| Assay | 98% |
| Optical activity | [α]20/D −153±5°, c = 5% in H2O |
| Optical purity | enantiomeric ratio: ≥99:1 (GC) |
| Melting point | 131-133 °C(lit.) |
Hazard statements
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | >190 °C / >374 °F |
| Water hazard class (WGK, DE) | 1 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-Mandelic acid used for?
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(R)-(−)-Mandelic acid is primarily used as a chiral resolving agent for separating racemic mixtures and as a chiral building block in asymmetric synthesis, particularly in the pharmaceutical industry.
What is the CAS number and chemical formula for (R)-(−)-Mandelic acid?
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The CAS number is 611-71-2 and the chemical formula is C6H5CH(OH)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-Mandelic acid with an assay of 98% and enantiomeric purity of ≥99:1. TSS does not represent this product as USP, BP, or EP grade.
How should (R)-(−)-Mandelic acid be handled safely?
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Handle with care, wearing safety goggles and gloves. Ensure adequate ventilation and use a P1 (EN143) or N95 respirator filter if needed. (R)-(−)-Mandelic acid is labelled with Danger, H318 (Causes serious eye damage).
Is (R)-(−)-Mandelic acid a controlled substance?
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The provided data does not indicate that (R)-(−)-Mandelic acid is a controlled substance.
How is (R)-(−)-Mandelic acid packed, shipped, and exported?
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Tech Serve Solutions expertly packs, ships, and exports chemicals globally, adhering to all international shipping regulations.
How can I request a sample or quote for (R)-(−)-Mandelic acid?
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To request a sample or a quotation for (R)-(−)-Mandelic acid, please contact our sales team through the website or by phone.
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