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(R)-(−)-N-(2,3-Epoxypropyl)phthalimide

CAS 181140-34-1C11H9NO3Chemical Synthesis

(R)-(−)-N-(2,3-Epoxypropyl)phthalimide (CAS: 181140-34-1, C11H9NO3) is a chiral epoxide building block with a molecular weight of 203.19. This compound is vital in asymmetric synthesis, serving as a precursor for complex chiral molecules. Its phthalimide protecting group and reactive epoxide moiety make it a versatile intermediate for introducing chiral centres in organic synthesis. It is supplied by TSS for research and chemical synthesis applications.

IUPAC
(R)-N-Glycidylphthalimide
Synonyms
C11H9NO3(R)-N-Glycidylphthalimide
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(R)-(−)-N-(2,3-Epoxypropyl)phthalimide (C11H9NO3) — chemical structure, CAS 181140-34-1; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral Building BlocksEpoxidesOrganic Building Blocks
01 /Applications

Chiral Building Block

Utilised as a key intermediate in the synthesis of enantiomerically pure compounds. Its inherent chirality allows for the construction of complex stereocentres in target molecules.

Asymmetric Synthesis

Serves as a valuable reagent in asymmetric synthesis, enabling the stereoselective formation of new chemical bonds. It is frequently employed in the preparation of chiral amines and other nitrogen-containing heterocycles.

Organic Synthesis Intermediate

Functions as a versatile intermediate in general organic synthesis. The epoxypropyl group readily undergoes nucleophilic ring-opening reactions, while the phthalimide can be cleaved to reveal a primary amine.

02 /Properties
Molecular weight203.19
Empirical formulaC11H9NO3
Assay≥99.0% (GC)
Optical purityee: 99% (HPLC)
Melting point100-102 °C
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
Danger

Hazard statements

  • H318Causes serious eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)2
Hazard codes (EU)Xi
Risk statements (R)41
Safety statements (S)26-39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
181140-34-1
MDL number
MFCD04973349
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (R)-(−)-N-(2,3-Epoxypropyl)phthalimide used for?

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(R)-(−)-N-(2,3-Epoxypropyl)phthalimide is primarily used as a chiral building block in asymmetric synthesis and as a versatile intermediate in organic chemistry for constructing complex chiral molecules.

What are the CAS number and formula for (R)-(−)-N-(2,3-Epoxypropyl)phthalimide?

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The CAS number for (R)-(−)-N-(2,3-Epoxypropyl)phthalimide is 181140-34-1, and its empirical formula is C11H9NO3.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (R)-(−)-N-(2,3-Epoxypropyl)phthalimide with an assay of ≥99.0% (GC) and an optical purity of ee: 99% (HPLC). This is a research grade product; TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.

How should (R)-(−)-N-(2,3-Epoxypropyl)phthalimide be handled safely?

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This compound can cause serious eye damage (H318). Always wear eyeshields, gloves, and a dust mask (type N95 or equivalent) when handling. Ensure good ventilation and avoid dust formation. In case of eye contact, rinse cautiously with water for several minutes, removing contact lenses if present and easy to do.

Is (R)-(−)-N-(2,3-Epoxypropyl)phthalimide a controlled substance?

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The provided data does not indicate that (R)-(−)-N-(2,3-Epoxypropyl)phthalimide is a controlled substance.

How is (R)-(−)-N-(2,3-Epoxypropyl)phthalimide packaged and exported?

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Tech Serve Solutions packages and exports chemicals according to international shipping regulations, ensuring safe transit. Specific packaging details can be provided upon request.

How can I request a quote or sample for (R)-(−)-N-(2,3-Epoxypropyl)phthalimide?

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To request a quote or a sample of (R)-(−)-N-(2,3-Epoxypropyl)phthalimide, please contact our sales department via the website or by telephone, providing your contact details and the required quantity.

Need (R)-(−)-N-(2,3-Epoxypropyl)phthalimide in a specific grade or volume?