(R)-(−)-N-Boc-3-pyrrolidinol
(R)-(−)-N-Boc-3-pyrrolidinol (CAS 109431-87-0, C9H17NO3) is a chiral heterocyclic building block with a molecular weight of 187.24. This compound serves as a valuable intermediate in asymmetric synthesis, specifically noted for its use in the preparation of ligands for nicotinic acetylcholine receptors. Supplied by Tech Serve Solutions, it is available at a purity of 98%, meeting the demands of sophisticated chemical research and development.
- IUPAC
- (R)-N-tert-Butoxycarbonyl-(−)-3-pyrrolidinol

Chiral Synthesis Intermediate
This compound is a key chiral building block employed in asymmetric synthesis. Its structure facilitates the stereoselective construction of complex molecules.
Ligand Synthesis for Receptor Studies
Specifically utilised in the synthesis of ligands designed for targeting nicotinic acetylcholine receptors. This application is critical in neurochemical research and drug discovery.
Heterocyclic Chemistry
As a pyrrolidine derivative, it is integral to heterocyclic chemistry, enabling the introduction of specific chiral centres into target compounds.
| Molecular weight | 187.24 |
|---|---|
| Empirical formula | C9H17NO3 |
| Assay | 98% |
| Optical activity | [α]20/D −26±1, c = 1 in methanol |
| Application | Used in synthesis of ligands for the nicotinic acetylcholine receptor.1 |
| Melting point | 62-65 °C(lit.) |


Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H400Very toxic to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38-50/53 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-N-Boc-3-pyrrolidinol used for?
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(R)-(−)-N-Boc-3-pyrrolidinol is used as a chiral building block in asymmetric synthesis, particularly for the preparation of ligands targeting nicotinic acetylcholine receptors.
What is the CAS number and formula for (R)-(−)-N-Boc-3-pyrrolidinol?
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The CAS number is 109431-87-0 and the empirical formula is C9H17NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-N-Boc-3-pyrrolidinol with an assay of 98%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should (R)-(−)-N-Boc-3-pyrrolidinol be handled safely?
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Handle with appropriate personal protective equipment including a dust mask (type N95 US recommended), eyeshields, and gloves. This compound is an irritant and harmful to aquatic life; avoid dust formation and release into the environment. Refer to the Safety Data Sheet for comprehensive handling information.
Is (R)-(−)-N-Boc-3-pyrrolidinol regulated or scheduled?
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Based on the provided data, there is no indication that (R)-(−)-N-Boc-3-pyrrolidinol is a controlled or scheduled substance.
How can I request a sample or quote for (R)-(−)-N-Boc-3-pyrrolidinol?
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Please contact our sales team via the website or direct email to request a sample or a quotation for (R)-(−)-N-Boc-3-pyrrolidinol.
How is (R)-(−)-N-Boc-3-pyrrolidinol packed and exported?
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(R)-(−)-N-Boc-3-pyrrolidinol is packed according to industry standards for chemical reagents and can be exported globally by Tech Serve Solutions.
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