(R)-(−)-N-Boc-3-N-Fmoc-aminopyrrolidine
(R)-(−)-N-Boc-3-N-Fmoc-aminopyrrolidine (CAS: 352530-40-6), with the molecular formula C24H28N2O4 and a molecular weight of 408.49 g/mol, is a chiral building block. It is primarily utilised in asymmetric synthesis and chemical synthesis. This compound serves as a valuable intermediate in the construction of complex organic molecules, particularly those requiring stereochemical control. Its structure features protected amine functionalities, making it amenable to diverse synthetic transformations.
- IUPAC
- (R)-(−)-1-(tert-Butoxycarbonyl)-3-N-(9-fluorenylmethoxycarbonyl)aminopyrrolidine

Asymmetric Synthesis
This chiral pyrrolidine derivative is employed as a building block in asymmetric synthesis. It facilitates the introduction of stereocentres into target molecules, crucial for the development of enantiomerically pure pharmaceuticals and fine chemicals.
Chemical Synthesis Intermediate
The compound serves as a versatile intermediate in multi-step organic synthesis. The orthogonal protection strategy (Boc and Fmoc) allows for selective deprotection and further functionalization, enabling the construction of complex heterocyclic structures.
Chiral Building Block
As a readily available chiral building block, it is integral in constructing molecules with defined stereochemistry. Its pyrrolidine core is a common motif in many biologically active compounds and catalysts.
Heterocyclic Chemistry
Its pyrrolidine scaffold makes it a useful starting material or intermediate in heterocyclic chemistry research and development. The protected amine groups offer sites for derivatization to explore novel heterocyclic systems.
| Molecular weight | 408.49 |
|---|---|
| Empirical formula | C24H28N2O4 |
| Assay | 97% |
| Storage temperature | −20°C |
| Melting point | 172-180 °C (DSC)(lit.)96-100 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-N-Boc-3-N-Fmoc-aminopyrrolidine used for?
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This compound is used as a chiral building block primarily in asymmetric synthesis and general chemical synthesis. It serves as a versatile intermediate for constructing complex organic molecules, particularly those requiring stereochemical control.
What are the CAS number and molecular formula for (R)-(−)-N-Boc-3-N-Fmoc-aminopyrrolidine?
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The CAS number is 352530-40-6 and the molecular formula is C24H28N2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 97%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should (R)-(−)-N-Boc-3-N-Fmoc-aminopyrrolidine be handled?
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Handling requires caution due to potential irritation. Use a dust mask type N95 (US), safety eyeshields, and gloves. Avoid breathing dust. Ensure adequate ventilation. Store at -20°C.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (R)-(−)-N-Boc-3-N-Fmoc-aminopyrrolidine.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales department through the website or by phone. Please reference the product name and CAS number (352530-40-6).
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