(R)-(+)-2-(Diphenylmethyl)pyrrolidine
(R)-(+)-2-(Diphenylmethyl)pyrrolidine (CAS: 22348-31-8) is a chiral organic compound with the formula C17H19N and a molecular weight of 237.34 g/mol. This molecule serves as a valuable chiral solvating agent, notably employed for the direct NMR determination of enantiomeric compositions in chiral carboxylic acids. Its specific stereochemistry makes it useful in asymmetric synthesis and as a component in chiral catalysis.
Chiral Solvating Agent
Utilised as an effective chiral solvating agent for the direct NMR analysis of enantiomeric composition in chiral carboxylic acids. Its distinct chiral environment allows for differentiation between enantiomers.
Asymmetric Synthesis
Serves as a building block or auxiliary in asymmetric synthesis. Its chiral pyrrolidine backbone is a common motif in chiral catalysts and ligands, facilitating enantioselective transformations.
NMR Spectroscopy
Facilitates the direct determination of enantiomeric excess (ee) of chiral carboxylic acids by NMR spectroscopy, a critical application in quality control and reaction monitoring.
| Molecular weight | 237.34 |
|---|---|
| Empirical formula | C17H19N |
| Assay | 97% |
| Density | 1.062 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5870(lit.) |
| Optical activity | [α]20/D +3.0°, c = 1% in chloroform |
| Application | Used as excellent chiral solvating agents to determine the enantiomeric composition of chiral carboxylic acids directly by NMR analysis.1 |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-2-(Diphenylmethyl)pyrrolidine used for?
+
(R)-(+)-2-(Diphenylmethyl)pyrrolidine is primarily used as a chiral solvating agent for the direct NMR determination of enantiomeric composition in chiral carboxylic acids. It also finds application in asymmetric synthesis.
What are the CAS number and chemical formula for (R)-(+)-2-(Diphenylmethyl)pyrrolidine?
+
The CAS number is 22348-31-8 and the chemical formula is C17H19N.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this chemical with an assay of 97%. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling recommendations for this compound?
+
This compound is classified as a Warning. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, should be used. Avoid breathing vapours.
How is (R)-(+)-2-(Diphenylmethyl)pyrrolidine packed, shipped, and exported?
+
Tech Serve Solutions offers professional packing, shipping, and global export services for laboratory chemicals and reagents, adhering to all relevant regulations.
How can I request a sample or quote for (R)-(+)-2-(Diphenylmethyl)pyrrolidine?
+
To request a sample or a quote, please contact our sales team through the website or by phone.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis