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(R)-(+)-2-Acetoxysuccinic anhydride

CAS 79814-40-7C6H6O5Chemical Synthesis

(R)-(+)-2-Acetoxysuccinic anhydride (CAS: 79814-40-7, C6H6O5, MW: 158.11) is a valuable chiral building block. As a carboxylic acid anhydride, it serves as a key intermediate in organic synthesis, particularly for introducing chiral succinate moieties. Its defined stereochemistry makes it suitable for asymmetric synthesis, enabling the creation of enantiomerically pure compounds for pharmaceutical and fine chemical applications. Tech Serve Solutions supplies this reagent for research and development purposes.

IUPAC
(R)-3-Acetoxy-dihydro-2,5-furandione,O-Acetyl-D-malic anhydride
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(R)-(+)-2-Acetoxysuccinic anhydride (C6H6O5) — chemical structure, CAS 79814-40-7; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisCarboxylic Acid AnhydridesChemical SynthesisChiral Building BlocksOrganic Building Blocks
01 /Applications

Chiral Synthesis

Serves as a chiral synthon for the preparation of enantiomerically enriched compounds. Its acetoxy and anhydride functionalities allow for diverse derivatization in asymmetric synthesis pathways.

Pharmaceutical Intermediates

A useful building block for constructing complex chiral molecules relevant to the pharmaceutical industry. It can be employed in the synthesis of active pharmaceutical ingredients (APIs) or their precursors.

Organic Building Block

Utilised as a versatile organic building block in academic and industrial research for the development of novel chemical entities. Its structure facilitates access to various functionalized succinic acid derivatives.

02 /Properties
Molecular weight158.11
Empirical formulaC6H6O5
Assay96%
Optical activity[α]20/D +27°, c = 1 in chloroform
Optical purityee: 99% (GLC)
Melting point56-58 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
79814-40-7
MDL number
MFCD00145214
PubChem substance
24867669
Beilstein registry
130824
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (R)-(+)-2-Acetoxysuccinic anhydride used for?

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(R)-(+)-2-Acetoxysuccinic anhydride is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the preparation of pharmaceuticals and fine chemicals.

What are the CAS number and formula for (R)-(+)-2-Acetoxysuccinic anhydride?

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The CAS number is 79814-40-7 and the empirical formula is C6H6O5.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (R)-(+)-2-Acetoxysuccinic anhydride with an assay of 96% and optical purity of ee: 99%. This is a research/technical grade material and is not supplied as USP, BP, EP, or any pharmacopoeia grade.

What are the main safety hazards associated with this chemical?

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This compound is classified as a GHS07 irritant, with the signal word 'Warning'. It carries hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used. Always consult the SDS for full safety information.

Is this chemical suitable for regulated applications like food or pharmaceuticals?

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This product is supplied for research and development purposes and is not intended for direct use in food, drug, or cosmetic applications. It is not supplied to any pharmacopoeia standards (USP, BP, EP).

How is this chemical shipped and exported?

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Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals and laboratory reagents, adhering to all necessary regulations for safe and compliant international shipping.

How can I request a sample or quote?

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To request a sample or a quote, please contact our sales team directly through our website or by calling our customer service line.

Need (R)-(+)-2-Acetoxysuccinic anhydride in a specific grade or volume?