(R)-(+)-2-Amino-1-fluoro-4-methyl-1,1-diphenylpentane
(R)-(+)-2-Amino-1-fluoro-4-methyl-1,1-diphenylpentane (CAS: 352535-74-1) is a chiral amine building block with a molecular weight of 271.37 g/mol. This fluorinated organic compound is valuable in asymmetric synthesis and various chemical synthesis pathways. It is supplied by TSS with an assay of 98% and high optical purity, making it suitable for advanced research and development in organic chemistry and pharmaceutical intermediate production.
- Synonyms
- (CH3)2CHCH2CH(NH2)C(F)(C6H5)2

Chiral Building Block in Organic Synthesis
This compound serves as a crucial chiral building block for constructing complex organic molecules. Its stereodefined structure is essential for developing enantiomerically pure target compounds in academic and industrial research.
Asymmetric Synthesis
The molecule's inherent chirality makes it a valuable reagent in asymmetric synthesis, enabling the formation of specific enantiomers in chemical reactions. This is particularly relevant in the development of stereoselective pharmaceuticals.
Pharmaceutical Intermediate Development
As a fluorinated amine, it can be incorporated into potential drug candidates, offering unique physicochemical properties. It aids in the synthesis of novel pharmaceutical intermediates where specific stereochemistry and fluorine substitution are desired.
| Molecular weight | 271.37 |
|---|---|
| Linear formula | (CH3)2CHCH2CH(NH2)C(F)(C6H5)2 |
| Assay | 98% |
| Optical activity | [α]20/D +51°, c = 1 in chloroform |
| Optical purity | ee: 99% (HPLC) |
| Melting point | 85-89 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-2-Amino-1-fluoro-4-methyl-1,1-diphenylpentane used for?
+
(R)-(+)-2-Amino-1-fluoro-4-methyl-1,1-diphenylpentane is primarily used as a chiral building block in organic synthesis and asymmetric synthesis, particularly for developing pharmaceutical intermediates.
What is the CAS number and formula for this compound?
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The CAS number is 352535-74-1. The linear formula is (CH3)2CHCH2CH(NH2)C(F)(C6H5)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-2-Amino-1-fluoro-4-methyl-1,1-diphenylpentane with an assay of 98% and an optical purity of ee: 99% (HPLC). It is supplied as a research-grade chemical and not represented as USP, BP, or EP grade.
What are the safety and handling precautions for this chemical?
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This compound is a Warning substance (GHS07) and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Always use appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes (P305 + P351 + P338).
How is this product packed, shipped, and exported by TSS?
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Tech Serve Solutions packs, ships, and exports chemicals globally, adhering to all relevant regulations for safe transport. Specific packing details are available upon request.
How can I request a sample or a quote for this product?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team through our website or by phone, providing the product name and CAS number (352535-74-1).
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