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(R)-(+)-2-Amino-3-phenyl-1-propanol

CAS 5267-64-1C6H5CH2CH(NH2)CH2OHChemical Synthesis

(R)-(+)-2-Amino-3-phenyl-1-propanol (CAS 5267-64-1, C6H5CH2CH(NH2)CH2OH) is a chiral amino alcohol with a molecular weight of 151.21 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in asymmetric synthesis. Its specific stereochemistry makes it useful for constructing complex chiral molecules, finding applications in the pharmaceutical and fine chemical industries where precise molecular architecture is essential.

IUPAC
D-Phenylalaninol
Synonyms
D-Phenylalaninol
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(R)-(+)-2-Amino-3-phenyl-1-propanol (C6H5CH2CH(NH2)CH2OH) — chemical structure, CAS 5267-64-1; Chemistry, fine chemical supplied by Tech Serve Solutions
Amino AlcoholsAsymmetric SynthesisChemical SynthesisChiral Building BlocksOrganic Building Blocks
01 /Applications

Chiral Building Block

(R)-(+)-2-Amino-3-phenyl-1-propanol is frequently employed as a chiral synthon in the preparation of enantiomerically pure compounds. Its defined stereocenter allows for stereoselective transformations, crucial in the development of active pharmaceutical ingredients.

Asymmetric Synthesis

This compound is instrumental in asymmetric synthesis, facilitating the creation of molecules with specific stereochemical configurations. It can be utilised as a chiral auxiliary or starting material for more complex chiral structures.

Pharmaceutical Intermediates

Its structure lends itself to the synthesis of various pharmaceutical intermediates, where chirality plays a critical role in biological activity and efficacy. Researchers leverage its properties to build targeted drug molecules.

Ligand Synthesis

The amino alcohol functionality can be incorporated into the design of chiral ligands for asymmetric catalysis. These ligands are vital for controlling the stereochemical outcome of catalysed reactions.

02 /Properties
Molecular weight151.21
Linear formulaC6H5CH2CH(NH2)CH2OH
Assay98%
Optical activity[α]/D +22.8°, c = 1.2 in 1 M HCl
Melting point93-95 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
Danger

Hazard statements

  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentEyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Transport (UN / ADR)UN 3259 8/PG 3
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)34
Safety statements (S)26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
5267-64-1
MDL number
MFCD00064298
PubChem substance
24857160
Beilstein registry
2208239
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (R)-(+)-2-Amino-3-phenyl-1-propanol used for?

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(R)-(+)-2-Amino-3-phenyl-1-propanol is primarily used as a chiral building block in asymmetric synthesis and for the preparation of pharmaceutical intermediates and chiral ligands.

What is the CAS number and chemical formula for (R)-(+)-2-Amino-3-phenyl-1-propanol?

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The CAS number is 5267-64-1 and the chemical formula is C6H5CH2CH(NH2)CH2OH.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (R)-(+)-2-Amino-3-phenyl-1-propanol with an assay of 98%. We do not represent this product as USP, BP, or EP grade.

What are the safety considerations for handling (R)-(+)-2-Amino-3-phenyl-1-propanol?

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This compound is classified as corrosive (Danger, H314 - Causes severe skin burns and eye damage). Appropriate personal protective equipment, including eyeshields, face shields, and suitable gloves, must be worn. Ensure adequate ventilation and handle with extreme care to avoid contact with skin, eyes, and clothing.

How is (R)-(+)-2-Amino-3-phenyl-1-propanol shipped and exported?

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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and can arrange for the shipment and export of (R)-(+)-2-Amino-3-phenyl-1-propanol according to international regulations.

How can I request a sample or quote for (R)-(+)-2-Amino-3-phenyl-1-propanol?

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You can request a sample or a quotation for (R)-(+)-2-Amino-3-phenyl-1-propanol by contacting our sales department through the website or by calling our main office.

Need (R)-(+)-2-Amino-3-phenyl-1-propanol in a specific grade or volume?