(R)-(+)-2-Bromo-3-methylbutyric acid
(R)-(+)-2-Bromo-3-methylbutyric acid (CAS: 76792-22-8) is a chiral building block with the molecular formula (CH3)2CHCH(Br)CO2H and a molecular weight of 181.03 g/mol. This organic compound is valuable in asymmetric synthesis due to its stereogenic centre. It is primarily utilised as a versatile intermediate in the synthesis of complex organic molecules, pharmaceuticals, and agrochemicals, offering a specific chiral configuration for advanced chemical manufacturing.
Chiral Building Block
(R)-(+)-2-Bromo-3-methylbutyric acid serves as a crucial chiral synthon in the preparation of enantiomerically pure compounds. Its defined stereochemistry is essential for constructing complex molecular architectures with specific biological activities.
Pharmaceutical Intermediate
This compound is employed in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its incorporation allows for the introduction of specific stereochemical features critical for drug efficacy and safety.
Organic Synthesis
As a functionalised carboxylic acid, it participates in a variety of organic transformations. The presence of the bromine atom and the chiral centre makes it a useful reagent for introducing specific structural motifs into target molecules.
| Molecular weight | 181.03 |
|---|---|
| Linear formula | (CH3)2CHCH(Br)CO2H |
| Assay | 96% |
| Boiling point | 90-100 °C/0.5 mmHg(lit.) |
| Optical activity | [α]22/D +21°, c = 37 in benzene |
| Melting point | 35-40 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H314Causes severe skin burns and eye damage
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 20/21/22-34 |
| Safety statements (S) | 26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-2-Bromo-3-methylbutyric acid used for?
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(R)-(+)-2-Bromo-3-methylbutyric acid is primarily used as a chiral building block and intermediate in asymmetric synthesis, particularly for pharmaceuticals and complex organic molecules.
What is the CAS number and chemical formula for (R)-(+)-2-Bromo-3-methylbutyric acid?
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The CAS number is 76792-22-8, and its linear chemical formula is (CH3)2CHCH(Br)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-2-Bromo-3-methylbutyric acid with a minimum assay of 96%. This product is not represented as USP, BP, or EP grade.
What are the primary safety hazards associated with (R)-(+)-2-Bromo-3-methylbutyric acid?
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This compound is classified as dangerous. It is harmful if swallowed, in contact with skin, or if inhaled, and causes severe skin burns and eye damage. Appropriate personal protective equipment, including gloves, goggles, and respiratory protection, must be used when handling it.
How is (R)-(+)-2-Bromo-3-methylbutyric acid typically packed and shipped?
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This chemical is packed in accordance with UN 3261, Class 8, Packing Group II regulations for hazardous materials. TSS exports fine chemicals globally, adhering to all relevant international shipping standards.
How can I request a quote or sample of (R)-(+)-2-Bromo-3-methylbutyric acid?
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To request a quote or sample, please contact our sales team via the website or provide your details through the product inquiry form. Specify the quantity required for accurate quotation.
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