(R)-(+)-2,2′-Dimethoxy-1,1′-binaphthalene
(R)-(+)-2,2′-Dimethoxy-1,1′-binaphthalene (CAS: 35294-28-1) is a chiral organic compound with the molecular formula C22H18O2 and a molecular weight of 314.38 g/mol. This BINOL derivative is recognised for its utility as a privileged ligand and chiral catalyst in asymmetric synthesis. Its specific enantiomeric form allows for high stereoselectivity in various chemical transformations, making it a valuable reagent in advanced organic chemistry research and development.
- IUPAC
- (R)-(+)-2,2′-Dimethoxy-1,1′-binaphthyl,(R)-1,1′-Bi-2-naphthyl dimethyl ether
- Synonyms
- 35294-28-1C22H18O2(R)-1,1′-Bi-2-naphthyl dimethyl ether

Asymmetric Catalysis
Serves as a crucial chiral ligand or catalyst in asymmetric reactions, facilitating the stereoselective synthesis of enantiomerically enriched compounds. Its structure is well-suited for applications in asymmetric oxidation, reduction, and carbon-carbon bond-forming reactions.
Chiral Auxiliaries
Can be employed as a chiral auxiliary, temporarily incorporated into a molecule to direct the stereochemical outcome of a reaction before being cleaved.
Research and Development
A key building block and reagent in academic and industrial research laboratories exploring novel synthetic methodologies and developing new chiral molecules.
| Molecular weight | 314.38 |
|---|---|
| Empirical formula | C22H18O2 |
| Assay | 97% |
| Optical activity | [α]20/D +52°, c = 1% in chloroform |
| Melting point | 227-231 °C(lit.) |

Hazard statements
- H318Causes serious eye damage
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 41 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-2,2′-Dimethoxy-1,1′-binaphthalene primarily used for?
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(R)-(+)-2,2′-Dimethoxy-1,1′-binaphthalene is primarily used as a chiral ligand or catalyst in asymmetric synthesis, enabling the stereoselective formation of enantiomerically enriched products in organic chemistry.
What are the CAS number and chemical formula for this compound?
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The CAS number for (R)-(+)-2,2′-Dimethoxy-1,1′-binaphthalene is 35294-28-1, and its empirical formula is C22H18O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-2,2′-Dimethoxy-1,1′-binaphthalene with an assay of 97%. We do not represent this product as meeting pharmacopoeia standards such as USP, BP, or EP.
How should (R)-(+)-2,2′-Dimethoxy-1,1′-binaphthalene be handled safely?
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This compound can cause serious eye damage (H318) and may cause long-lasting harmful effects to aquatic life (H413). Handle with appropriate personal protective equipment including a dust mask (type N95), eyeshields, and gloves. Ensure good ventilation and avoid release into the environment.
Is this chemical suitable for use in pharmaceutical manufacturing?
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While used in research related to pharmaceutical intermediates, this product is supplied at a 97% assay and is not certified to meet specific pharmacopoeia (USP, BP, EP) standards. Further purification or quality assessment may be required for direct pharmaceutical applications.
How is this chemical packed and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures that (R)-(+)-2,2′-Dimethoxy-1,1′-binaphthalene is appropriately packaged for safe transport and adheres to all necessary export regulations for chemical shipments worldwide.
How can I request a sample or quote for this chemical?
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To request a sample or a quotation for (R)-(+)-2,2′-Dimethoxy-1,1′-binaphthalene, please contact our sales department through the details provided on the Tech Serve Solutions website.
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