4-Chlorothiophenol
4-Chlorothiophenol (CAS: 106-54-7), with the molecular formula ClC6H4SH and a molecular weight of 144.62 g/mol, is a key organic building block. This sulfur compound, also known as 4-chlorobenzenethiol, is primarily utilised in chemical synthesis. It finds application in modifying polymers, such as poly(vinyl chloride), and in the creation of new materials with specific halogenated properties.
- IUPAC
- 4-Chlorobenzenethiol,4-Chlorophenyl mercaptan
- Synonyms
- 4-Chlorobenzenethiol4-Chlorophenyl mercaptan

Polymer Modification
4-Chlorothiophenol serves as a valuable reagent for modifying existing polymer structures. It has been employed in the chemical alteration of poly(vinyl chloride), introducing specific functional groups.
Synthesis of Halogenated Polymers
This compound is instrumental in the synthesis of novel polymers incorporating halogen atoms. Its reactivity allows for the controlled creation of poly(vinyl chloride) derivatives with enhanced or altered properties.
Organic Synthesis Reagent
As a functionalised thiol, 4-Chlorothiophenol is a versatile building block in organic chemistry. It can participate in various coupling reactions and other transformations for the construction of complex molecules.
| Molecular weight | 144.62 |
|---|---|
| Linear formula | ClC6H4SH |
| Assay | 97% |
| Boiling point | 205-207 °C(lit.) |
| Solubility | methanol: soluble |
| Application | 4-Chlorothiophenol was used to modify poly(vinyl chloride) and to synthesize poly(vinyl chloride) with halogen groups1. |
| Melting point | 49-51 °C(lit.) |


Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 81 °C / 177.8 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chlorothiophenol used for?
+
4-Chlorothiophenol is used in chemical synthesis, particularly for modifying poly(vinyl chloride) and for the synthesis of polymers containing halogen groups.
What are the CAS number and chemical formula for 4-Chlorothiophenol?
+
The CAS number for 4-Chlorothiophenol is 106-54-7, and its chemical formula is ClC6H4SH.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 4-Chlorothiophenol with an assay of 97%. This product is not represented as USP, BP, or EP grade.
How should 4-Chlorothiophenol be handled safely?
+
4-Chlorothiophenol is classified as Danger, with hazard statements H302 (Harmful if swallowed) and H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection, is essential. Handle only in a well-ventilated area or under a fume hood.
How is 4-Chlorothiophenol packed, shipped, and exported?
+
4-Chlorothiophenol is supplied in appropriate packaging for safe transport and is available for global export by Tech Serve Solutions. Specific shipping details, including UN 3261 classification, are available upon request.
How can I request a sample or quote for 4-Chlorothiophenol?
+
To request a sample or a quote for 4-Chlorothiophenol, please contact our sales team via the website or direct inquiry channels.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis