1-(4-Trifluoromethylphenyl)piperazine
1-(4-Trifluoromethylphenyl)piperazine (CAS: 30459-17-7, C11H13F3N2) is a valuable heterocyclic building block with a molecular weight of 230.23 g/mol. This compound serves as a key intermediate in organic synthesis, particularly within the pharmaceutical and agrochemical industries. Its trifluoromethylphenyl and piperazine moieties offer versatile reactivity for constructing complex molecules, making it an essential reagent for researchers and process chemists.
- IUPAC
- 1-(α,α,α-Trifluoro-p-tolyl)piperazine
- Synonyms
- 1-(α,α,α-Trifluoro-p-tolyl)piperazine
Pharmaceutical Intermediate
This compound is frequently employed as a building block in the synthesis of active pharmaceutical ingredients (APIs). Its structure is amenable to modifications for developing novel therapeutic agents.
Agrochemical Synthesis
It serves as a precursor in the development of new pesticides and herbicides. The trifluoromethyl group can enhance the efficacy and metabolic stability of agrochemical compounds.
Organic Synthesis Reagent
1-(4-Trifluoromethylphenyl)piperazine is a versatile reagent for general organic synthesis, enabling the introduction of the trifluoromethylphenylpiperazine fragment into various molecular architectures.
Material Science
Potential applications exist in the development of specialized materials where the unique electronic and steric properties of the molecule can be exploited.
| Molecular weight | 230.23 |
|---|---|
| Empirical formula | C11H13F3N2 |
| Assay | ≥98.0% (GC) |
| Melting point | 88-92 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(4-Trifluoromethylphenyl)piperazine used for?
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It is primarily used as a building block and intermediate in pharmaceutical and agrochemical synthesis, as well as in general organic synthesis.
What is the CAS number and formula for 1-(4-Trifluoromethylphenyl)piperazine?
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The CAS number is 30459-17-7, and the empirical formula is C11H13F3N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-(4-Trifluoromethylphenyl)piperazine with an assay of ≥98.0% (GC). We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade unless explicitly stated.
How should 1-(4-Trifluoromethylphenyl)piperazine be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust. It is classified as causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335).
Can Tech Serve Solutions export 1-(4-Trifluoromethylphenyl)piperazine?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents.
How can I request a quote or sample for 1-(4-Trifluoromethylphenyl)piperazine?
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Please use the contact form on our website or call our sales team to request a quote or sample for 1-(4-Trifluoromethylphenyl)piperazine.
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