1-(4-bromophenyl)piperazine
1-(4-Bromophenyl)piperazine (CAS 66698-28-0) is a halogenated arylpiperazine building block with the molecular formula C10H13BrN2 and a molar mass of 241.13 g/mol. Supplied as a solid of around 95% assay, it combines a reactive aryl bromide with a secondary piperazine nitrogen, making it a versatile intermediate for chemical synthesis. Tech Serve Solutions supplies and exports this heterocyclic reagent to research, discovery and fine-chemical laboratories worldwide.
- IUPAC
- 1-(4-bromophenyl)piperazine
- Synonyms
- 1-(4-Bromophenyl)piperazine4-(4-Bromophenyl)piperazine1-(4-bromophenyl)piperazine, 66698-28-0MFCD00130198

Heterocyclic building block
Serves as a piperazine-based scaffold in chemical synthesis, where the secondary nitrogen of the piperazine ring is readily functionalised through alkylation, acylation or sulfonylation to build more elaborate molecules.
Cross-coupling substrate
The para-bromophenyl group provides a reactive site for palladium-catalysed cross-coupling reactions such as Suzuki, Buchwald-Hartwig and related transformations, allowing introduction of aryl, amino and other substituents.
Pharmaceutical and medicinal chemistry intermediate
Arylpiperazines are a common structural motif in medicinal chemistry. This compound is used in discovery and process research as a starting material for the preparation of candidate molecules and analogues.
Laboratory research reagent
Used as a defined reference and reagent in synthetic and analytical laboratories where a characterised arylpiperazine of known assay and melting range is required.
| Molecular weight | 241.13 |
|---|---|
| Empirical formula | C10H13BrN2 |
| Assay | 95% |
| Storage temperature | 2-8°C |
| Melting point | 91-95 °C |

Hazard statements
- H302Harmful if swallowed
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Water hazard class (WGK, DE) | 1 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(4-bromophenyl)piperazine used for?
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It is used mainly as a synthetic building block and intermediate. The reactive aryl bromide and the secondary piperazine nitrogen make it useful for cross-coupling reactions and for constructing arylpiperazine scaffolds in chemical synthesis and medicinal chemistry research.
What is the CAS number and molecular formula of 1-(4-bromophenyl)piperazine?
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The CAS number is 66698-28-0 and the molecular formula is C10H13BrN2, with a molecular weight of 241.13 g/mol. The MDL number is MFCD00130198.
What grade and purity does Tech Serve Solutions supply?
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It is supplied as a research and synthesis grade material with an assay of approximately 95% and a melting point of 91-95 °C. We do not represent it as USP, BP or EP pharmacopoeial grade; a certificate of analysis can be provided with each batch.
What are the safety and handling requirements for 1-(4-bromophenyl)piperazine?
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It carries GHS07 with the signal word Warning. The hazards are H302, H312 and H332 — harmful if swallowed, in contact with skin or if inhaled. Wear protective gloves and suitable protection (P280), avoid generating dust, and consult the Safety Data Sheet before use. The German water hazard class is WGK 1.
How should 1-(4-bromophenyl)piperazine be stored?
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Store the material refrigerated at 2-8 °C in a tightly closed container, kept dry and away from incompatible substances. Refer to the Safety Data Sheet for full storage and stability guidance.
How is 1-(4-bromophenyl)piperazine packed, shipped and exported?
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It is packed in laboratory and bulk quantities in sealed, appropriately labelled containers suited to a temperature-sensitive solid, with documentation and transport classification arranged for compliant domestic and international shipment. Tech Serve Solutions exports to customers worldwide.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, packaging and destination, and our team will respond with availability, lead time and quotation. Samples can be arranged for qualified laboratory and industrial customers.
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