Hydroxyzine dihydrochloride
Hydroxyzine dihydrochloride (CAS: 2192-20-3; C21H27ClN2O2 · 2HCl) is a white to off-white crystalline powder. With a molecular weight of 447.83 g/mol, this compound is soluble in water, alcohol, and chloroform. It is primarily utilized as a research chemical in various biological and chemical investigations, particularly within the fields of cell biology and drug metabolism studies.

Pharmacological Research
Hydroxyzine dihydrochloride serves as a valuable tool in research settings for studying antihistaminic and anxiolytic properties. It is employed in in-vitro experiments to investigate cellular responses and signalling pathways.
Drug Metabolism Studies
This compound is used in studies related to drug and xenobiotic metabolism, aiding researchers in understanding enzymatic processes and metabolic transformations. Its involvement in multi-drug resistance research is also notable.
Biochemical Investigations
As a bioactive small molecule, hydroxyzine dihydrochloride is utilized in biochemical assays and as a reagent in laboratory settings for various scientific explorations.
| Molecular weight | 447.83 |
|---|---|
| Empirical formula | C21H27ClN2O2 · 2HCl |
| Assay | ≥98% |
| Form | powder |
| Solubility | H2O: solublealcohol: solublechloroform: soluble |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Hydroxyzine dihydrochloride used for?
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Hydroxyzine dihydrochloride is used in research for pharmacological studies, including investigations into its antihistaminic and anxiolytic properties, as well as in drug and xenobiotic metabolism research.
What are the CAS number and formula for Hydroxyzine dihydrochloride?
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The CAS number for Hydroxyzine dihydrochloride is 2192-20-3, and its formula is C21H27ClN2O2 · 2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Hydroxyzine dihydrochloride with an assay of ≥98%. This product is intended for research and laboratory use and is not supplied as USP, BP, or EP grade.
How should Hydroxyzine dihydrochloride be handled safely?
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Hydroxyzine dihydrochloride is a Warning substance (H302, H315, H319, H335). Handle with appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves, in a well-ventilated area to avoid dust inhalation and skin/eye contact.
Is Hydroxyzine dihydrochloride a controlled substance?
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Based on the provided data, there is no indication that Hydroxyzine dihydrochloride is a controlled substance.
How is Hydroxyzine dihydrochloride packed and shipped?
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Hydroxyzine dihydrochloride is typically supplied as a powder. Details on specific packaging for export and shipping can be provided upon request.
How can I request a sample or quote for Hydroxyzine dihydrochloride?
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To request a sample or quote for Hydroxyzine dihydrochloride, please contact our sales department through the website or by phone, providing your specific requirements.
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