(S)-(+)-2-(Methoxymethyl)pyrrolidine
(S)-(+)-2-(Methoxymethyl)pyrrolidine (CAS 63126-47-6) is a chiral pyrrolidine derivative with the formula C6H13NO and a molecular weight of 115.17 g/mol. This compound serves as a valuable building block and catalyst in asymmetric synthesis. Its enantiopurity makes it particularly useful for stereoselective reactions, facilitating the synthesis of complex molecules in pharmaceutical and fine chemical industries.
- IUPAC
- O-Methyl-L-prolinol,SMP
- Synonyms
- O-Methyl-L-prolinol,SMP
Chiral Ligand in Asymmetric Catalysis
This compound can act as a chiral ligand in various metal-catalyzed asymmetric transformations. Its structure allows for the induction of enantioselectivity in reactions such as alkylations, additions, and reductions, leading to chiral products.
Organocatalyst in Asymmetric Synthesis
As a proline-derived organocatalyst, (S)-(+)-2-(Methoxymethyl)pyrrolidine can promote a range of stereoselective reactions, including Michael additions, aldol reactions, and Mannich reactions, without the need for metal catalysts.
Building Block for Pharmaceutical Intermediates
The chiral nature of this pyrrolidine derivative makes it a useful synthon for constructing complex chiral molecules, including pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
| Molecular weight | 115.17 |
|---|---|
| Empirical formula | C6H13NO |
| Assay | 99% |
| Grade | purum |
| Boiling point | 62 °C/40 mmHg(lit.) |
| Density | 0.933 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4457(lit.) |
| Optical activity | [α]20/D +2.4°, c = 2 in benzene |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 45 °C / 113 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-2-(Methoxymethyl)pyrrolidine used for?
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(S)-(+)-2-(Methoxymethyl)pyrrolidine is primarily used as a chiral building block, ligand, or organocatalyst in asymmetric synthesis for the preparation of enantiomerically enriched compounds, particularly in the pharmaceutical and fine chemical sectors.
What are the CAS number and formula for (S)-(+)-2-(Methoxymethyl)pyrrolidine?
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The CAS number for (S)-(+)-2-(Methoxymethyl)pyrrolidine is 63126-47-6, and its empirical formula is C6H13NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-2-(Methoxymethyl)pyrrolidine with a purity of 99% (purum grade). We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should (S)-(+)-2-(Methoxymethyl)pyrrolidine be handled safely?
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(S)-(+)-2-(Methoxymethyl)pyrrolidine is flammable (H226) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Use appropriate personal protective equipment including eyeshields, gloves, and respiratory protection, and handle in a well-ventilated area away from ignition sources.
How is (S)-(+)-2-(Methoxymethyl)pyrrolidine packed and shipped?
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This chemical is typically packed in suitable containers for export, adhering to international shipping regulations for hazardous materials, including UN 1993 classification.
How can I request a sample or quote for (S)-(+)-2-(Methoxymethyl)pyrrolidine?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team via our website or direct contact details, specifying the product name and CAS number.
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