(S)-(+)-2-(Trifluoromethyl)pyrrolidine
(S)-(+)-2-(Trifluoromethyl)pyrrolidine (CAS: 119580-41-5, Formula: C5H8F3N, MW: 139.12 g/mol) is a chiral heterocyclic building block. Its trifluoromethyl group imparts unique electronic and steric properties, making it valuable in asymmetric synthesis and complex molecule construction. Supplied by Tech Serve Solutions with an assay of 97%, it is primarily utilised as a reagent and intermediate in chemical research and development.
Asymmetric Synthesis
This chiral pyrrolidine derivative serves as a crucial building block in enantioselective synthesis. Its structure allows for the introduction of stereochemical control in the creation of complex organic molecules.
Pharmaceutical Intermediates
The compound is employed in the synthesis of novel pharmaceutical agents. Its trifluoromethyl-substituted pyrrolidine core can be incorporated into drug candidates to potentially enhance metabolic stability and binding affinity.
Chemical Research and Development
As a versatile heterocyclic scaffold, (S)-(+)-2-(Trifluoromethyl)pyrrolidine is utilised in academic and industrial research for exploring new synthetic methodologies and discovering novel chemical entities.
| Molecular weight | 139.12 |
|---|---|
| Empirical formula | C5H8F3N |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 29-33 °C |
Hazard statements
- H228Flammable solid
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 29 °C / 84.2 °F |
| Transport (UN / ADR) | UN 1325 4.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-2-(Trifluoromethyl)pyrrolidine primarily used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the development of new chemical entities, particularly in pharmaceutical research.
What are the CAS number and formula for (S)-(+)-2-(Trifluoromethyl)pyrrolidine?
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The CAS number is 119580-41-5 and the empirical formula is C5H8F3N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-2-(Trifluoromethyl)pyrrolidine with an assay of 97%. This is a technical/research grade chemical and is not represented as USP, BP, EP or other pharmacopoeia grades.
How should (S)-(+)-2-(Trifluoromethyl)pyrrolidine be handled?
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This compound is a flammable solid and is harmful if swallowed, causes skin irritation, serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. Store at 2-8°C and keep away from heat and open flames.
How is (S)-(+)-2-(Trifluoromethyl)pyrrolidine packed and shipped?
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This chemical is shipped as a UN 1325, Hazard Class 4.1, Packing Group II. Specific packing and export details are available upon request.
How can I request a sample or quote for (S)-(+)-2-(Trifluoromethyl)pyrrolidine?
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Please contact our sales team to request a sample or obtain a quotation for (S)-(+)-2-(Trifluoromethyl)pyrrolidine.
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