(S)-(+)-2-(Dibenzylamino)-1-propanol

CAS 60479-65-4(C6H5CH2)2NCH(CH3)CH2OHChemical Synthesis

(S)-(+)-2-(Dibenzylamino)-1-propanol (CAS 60479-65-4) is a chiral organic building block with a molecular weight of 255.35 g/mol. Its linear formula is (C6H5CH2)2NCH(CH3)CH2OH. This compound is primarily utilised as a key intermediate in the synthesis of complex molecules, notably within the pharmaceutical industry for the development of HIV protease inhibitors. Its specific stereochemistry makes it valuable in asymmetric synthesis.

Email us

(S)-(+)-2-(Dibenzylamino)-1-propanol ((C6H5CH2)2NCH(CH3)CH2OH) — chemical structure, CAS 60479-65-4; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino AlcoholsAsymmetric SynthesisChemical SynthesisChiral Building BlocksOrganic Building Blocks

01 /Applications

Synthesis of HIV Protease Inhibitors

This chiral amino alcohol serves as a crucial building block in the multi-step synthesis of pharmaceutical agents designed to inhibit HIV protease. Its stereochemical integrity is vital for the efficacy of the final drug product.

Asymmetric Synthesis

The defined stereocenter of (S)-(+)-2-(Dibenzylamino)-1-propanol makes it a valuable chiral auxiliary or precursor in asymmetric synthesis. It enables the controlled introduction of chirality in organic molecules.

Organic Synthesis Intermediate

As a functionalised organic molecule, it can be employed in various chemical synthesis pathways, providing a scaffold for constructing more elaborate organic structures.

02 /Properties

Molecular weight	255.35
Linear formula	(C6H5CH2)2NCH(CH3)CH2OH
Assay	99%
Boiling point	142-148 °C/0.1 mmHg(lit.)
Optical activity	[α]20/D +90°, c = 1 in chloroform
Application	Building block for the synthesis of HIV protease inhibitors.1,2,3,4,5,6
Melting point	46-48 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

60479-65-4

MDL number

MFCD00191985

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(+)-2-(Dibenzylamino)-1-propanol primarily used for?

It is primarily used as a building block in the synthesis of HIV protease inhibitors and in asymmetric synthesis.

What are the CAS number and formula for (S)-(+)-2-(Dibenzylamino)-1-propanol?

The CAS number is 60479-65-4 and the linear formula is (C6H5CH2)2NCH(CH3)CH2OH.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical with an assay of 99%. We do not represent it as USP, BP, or EP grade.

What are the safety considerations for handling (S)-(+)-2-(Dibenzylamino)-1-propanol?

This compound is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used. Ensure good ventilation.