1-Acetylindole
1-Acetylindole (CAS 576-15-8), with the molecular formula C10H9NO and a molar mass of 159.18 g/mol, is a versatile organic compound. It serves as a key intermediate in the synthesis of various biologically active molecules. Its applications include the preparation of antimycobacterial agents and cyclin-dependent kinase (CDK2) inhibitors, as well as participation in oxidative cross-coupling reactions. Available from Tech Serve Solutions, it meets stringent quality standards for research and development.
- IUPAC
- NSC 521758
Synthesis of Antimycobacterial Agents
1-Acetylindole acts as a crucial reactant in the multi-step synthesis of compounds exhibiting antimycobacterial activity. This application is vital for developing new treatments against tuberculosis and other mycobacterial infections.
Development of CDK2 Inhibitors
This indole derivative is employed as a precursor in the preparation of cyclin-dependent kinase 2 (CDK2) inhibitors. These inhibitors are of significant interest in oncology research for their potential to regulate cell cycle progression in cancer cells.
Cross-Coupling Reactions
1-Acetylindole is utilised as a substrate in C3-C3 oxidative cross-coupling reactions. This facilitates the formation of new carbon-carbon bonds, enabling the construction of more complex molecular architectures.
| Molecular weight | 159.18 |
|---|---|
| Empirical formula | C10H9NO |
| Assay | 98% |
| Boiling point | 123-125 °C/8 mmHg(lit.) |
| Density | 1.387 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.607(lit.) |
| Storage temperature | 2-8°C |
| Application | Reactant for preparation of:• Antimycobacterial agents1• Cyclin-dependent kinase (CDK2) inhibitors2Reactant for:• C3-C3 oxidative cross-coupling reactions3 |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Flash point | >113 °C / >235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Acetylindole primarily used for?
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1-Acetylindole is primarily used as a reactant in chemical synthesis, particularly for preparing antimycobacterial agents, cyclin-dependent kinase (CDK2) inhibitors, and in oxidative cross-coupling reactions.
What are the CAS number and molecular formula for 1-Acetylindole?
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The CAS number for 1-Acetylindole is 576-15-8, and its molecular formula is C10H9NO.
What grade and purity does Tech Serve Solutions supply for 1-Acetylindole?
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Tech Serve Solutions supplies 1-Acetylindole with a purity of 98% (assay). This product is intended for laboratory and research use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 1-Acetylindole be handled and stored safely?
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1-Acetylindole should be handled with appropriate personal protective equipment, including eyeshields and gloves. It has a flash point above 113 °C (235.4 °F) and should be stored at a temperature of 2-8°C.
How is 1-Acetylindole packed, shipped, and exported?
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1-Acetylindole is carefully packed according to international shipping regulations and is available for global export by Tech Serve Solutions.
How can I request a sample or a quote for 1-Acetylindole?
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To request a sample or obtain a quote for 1-Acetylindole, please contact the Tech Serve Solutions sales team through our website or by phone.
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