1-Acetylpiperidine-4-carboxylic acid
1-Acetylpiperidine-4-carboxylic acid (CAS: 25503-90-6), with the molecular formula C8H13NO3 and a molecular weight of 171.19 g/mol, is a vital heterocyclic building block. It serves as a key reactant in the synthesis of various complex organic molecules, including triazole derivatives, antiproliferative agents, CDK inhibitors, and CCR5 antagonists. This compound is essential for advanced chemical synthesis and the development of novel pharmaceutical agents.
- IUPAC
- N-Acetylisonipecotic acid
Synthesis of Triazole Derivatives
1-Acetylpiperidine-4-carboxylic acid is employed as a reactant in the synthesis of diverse triazole derivatives, which are valuable scaffolds in medicinal chemistry.
Development of Antiproliferative Agents
This compound functions as a building block for the creation of antiproliferative agents, contributing to the research and development of cancer therapeutics.
CDK Inhibitor Synthesis
It is utilized in the synthetic routes for Cyclin-Dependent Kinase (CDK) inhibitors, crucial targets in cell cycle regulation research and drug discovery.
CCR5 Antagonist Precursor
The carboxylic acid is a precursor for the synthesis of CCR5 antagonists, which are investigated for their potential in HIV treatment strategies.
nhNK1 Antagonist Development
It serves as a reactant in the preparation of neurokinin-1 (NK1) receptor antagonists, relevant for neurological and inflammatory condition research.
Piperidine Derivative Synthesis
1-Acetylpiperidine-4-carboxylic acid is a key intermediate in the synthesis of various functionalised piperidine derivatives, important in organic synthesis.
| Molecular weight | 171.19 |
|---|---|
| Empirical formula | C8H13NO3 |
| Assay | 97% |
| Application | Reactant for synthesis of:• Triazole derivatives1• Antiproliferative agents2• CDK inhibitors3• CCR5 antagonists for HIV treatment4• nhNK1 antagonists5• Piperidine derivatives6 |
| Melting point | 180-184 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38-43 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Acetylpiperidine-4-carboxylic acid used for?
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1-Acetylpiperidine-4-carboxylic acid is primarily used as a reactant and building block in the synthesis of various organic compounds, including triazole derivatives, antiproliferative agents, CDK inhibitors, CCR5 antagonists, and other piperidine derivatives.
What is the CAS number and molecular formula for 1-Acetylpiperidine-4-carboxylic acid?
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The CAS number for 1-Acetylpiperidine-4-carboxylic acid is 25503-90-6, and its molecular formula is C8H13NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Acetylpiperidine-4-carboxylic acid with an assay of 97%. We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.
What are the safety and handling precautions for this chemical?
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1-Acetylpiperidine-4-carboxylic acid is classified as harmful if swallowed and can cause skin irritation, allergic skin reaction, serious eye irritation, and respiratory irritation. Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, faceshields, and gloves. Ensure adequate ventilation and avoid breathing dust.
How is 1-Acetylpiperidine-4-carboxylic acid packed and exported?
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1-Acetylpiperidine-4-carboxylic acid is carefully packed to ensure product integrity during transit and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for 1-Acetylpiperidine-4-carboxylic acid?
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To request a sample or a quote for 1-Acetylpiperidine-4-carboxylic acid, please contact our sales team through the website or by phone.
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