1-Acetylimidazole
1-Acetylimidazole (CAS: 2466-76-4, C5H6N2O) is a versatile chemical building block with a molecular weight of 110.11 g/mol. This compound serves as a relatively specific reagent for the acetylation of tyrosyl residues, making it valuable in protein modification and structural analysis. It is also employed in the synthesis of annulated imidazole derivatives, finding utility in organic synthesis and medicinal chemistry research.

Tyrosyl Residue Acetylation
1-Acetylimidazole is a selective reagent for acetylating tyrosyl residues in proteins. This application is crucial in biochemical studies for understanding protein structure and function, and for proteomics research.
Synthesis of Annulated Imidazoles
The compound is utilized as a key intermediate in the synthesis of various annulated imidazole derivatives. These structures are of interest in medicinal chemistry for their potential biological activities.
Heterocyclic Building Block
As a functionalised imidazole, 1-Acetylimidazole acts as a valuable building block in organic synthesis. Its structure allows for further elaboration into more complex heterocyclic systems.
Chemical Synthesis Reagent
Its reactivity profile makes 1-Acetylimidazole a useful reagent in general chemical synthesis, particularly for introducing the acetylimidazole moiety into target molecules.
| Molecular weight | 110.11 |
|---|---|
| Empirical formula | C5H6N2O |
| Assay | 98% |
| Solubility | water: soluble50 mg/mL, clear, colorless |
| Storage temperature | 2-8°C |
| Application | Relatively specific reagent for tyrosyl residue acetylation. Reagent used in the synthesis of annulated imidazole derivatives. |
| Melting point | 99-105 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Acetylimidazole used for?
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1-Acetylimidazole is primarily used as a reagent for the selective acetylation of tyrosyl residues in proteins and in the synthesis of annulated imidazole derivatives.
What is the CAS number and chemical formula for 1-Acetylimidazole?
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The CAS number is 2466-76-4, and the chemical formula is C5H6N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Acetylimidazole with a minimum assay of 98%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated in the product documentation.
What are the safety and handling precautions for 1-Acetylimidazole?
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Handle 1-Acetylimidazole with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified under WGK Germany 3, indicating a high hazard to water.
How is 1-Acetylimidazole packed, shipped, and exported?
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Tech Serve Solutions offers 1-Acetylimidazole packaged securely for transport. We are a global supplier and exporter, adhering to all relevant shipping regulations for chemical products.
How can I request a quote or sample for 1-Acetylimidazole?
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To request a quote or sample of 1-Acetylimidazole, please contact our sales team through the website or by phone. Please specify your required quantity and intended use.
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