1-Acetyl-6-aminoindoline
1-Acetyl-6-aminoindoline (CAS: 62368-29-0, C10H12N2O) is a heterocyclic organic compound with a molecular weight of 176.22 g/mol. This indoline derivative serves as a valuable building block in chemical synthesis. It is primarily utilised as a reactant in the preparation of various biologically active molecules, including receptor antagonists and antiviral agents.
- IUPAC
- 1-(6-Amino-2,3-dihydro-indol-1-yl)ethanone,1-Acetyl-6-amino-2,3-dihydroindole,6-Amino-N-acetylindoline,NSC 87623
- Synonyms
- 1-(6-Amino-2,3-dihydro-indol-1-yl)ethanone1-Acetyl-6-amino-2,3-dihydroindole6-Amino-N-acetylindolineNSC 87623
TRPV1 Antagonist Synthesis
1-Acetyl-6-aminoindoline is employed as a key intermediate in the synthesis of transient receptor potential cation channel V1 (TRPV1) antagonists, compounds investigated for various therapeutic applications.
Antiviral Research
This compound acts as a reactant in the development of inhibitors targeting the binding of the human immunodeficiency virus (HIV) envelope glycoprotein gp120 to the CD4 receptor, contributing to antiviral research efforts.
Antiproliferative Agent Development
It serves as a precursor in the synthesis of antiproliferative agents, which are compounds studied for their potential to inhibit cell growth and proliferation.
Serotonin Receptor Antagonist Synthesis
1-Acetyl-6-aminoindoline is utilised in the preparation of serotonin 5-HT2C/2B receptor antagonists, contributing to the synthesis of compounds targeting these neurological pathways.
| Molecular weight | 176.22 |
|---|---|
| Empirical formula | C10H12N2O |
| Storage temperature | 2-8°C |
| Application | Reactant for preparation of:• Transient receptor potential cation channel V1 (TRPV1) antagonists1• Inhibitor of the human immunodeficiency virus (HIV) envelope glycoprotein gp120 binding to the cluster of differentiation 4 (CD4) receptor2• Antiproliferative agents3• Serotonin 5-HT2C/2B receptor antagonists4 |
Hazard statements
- H302Harmful if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Acetyl-6-aminoindoline used for?
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1-Acetyl-6-aminoindoline is used as a reactant and building block in chemical synthesis, notably for preparing TRPV1 antagonists, HIV gp120 inhibitors, antiproliferative agents, and serotonin 5-HT2C/2B receptor antagonists.
What are the CAS number and formula for 1-Acetyl-6-aminoindoline?
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The CAS number is 62368-29-0 and the empirical formula is C10H12N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Acetyl-6-aminoindoline as a research-grade chemical. We do not represent it as USP, BP, or EP grade.
How should 1-Acetyl-6-aminoindoline be handled safely?
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1-Acetyl-6-aminoindoline is classified as harmful if swallowed (H302) and causes serious eye irritation (H319). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation.
How is 1-Acetyl-6-aminoindoline packed, shipped, and exported?
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1-Acetyl-6-aminoindoline is carefully packed for transit and available for global export by Tech Serve Solutions.
How can I request a sample or quote for 1-Acetyl-6-aminoindoline?
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To request a sample or quote for 1-Acetyl-6-aminoindoline, please contact our sales team via the website or your dedicated account manager.
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