Fmoc-Val-OH
Fmoc-Val-OH (CAS 68858-20-8), chemically known as N-(9-Fluorenylmethoxycarbonyl)-L-valine, is a crucial derivative of the amino acid valine. With the molecular formula C20H21NO4 and a molecular weight of 339.39 g/mol, it is a key building block in peptide synthesis. This compound plays a vital role in solid-phase peptide synthesis (SPPS) and other organic chemistry applications requiring protected amino acids for controlled chain elongation.
- IUPAC
- N-(9-Fluorenylmethoxycarbonyl)-L-valine,Fmoc-L-valine
- Synonyms
- N-(9-Fluorenylmethoxycarbonyl)-L-valineFmoc-L-valine
Peptide Synthesis
Fmoc-Val-OH is widely used in solid-phase peptide synthesis (SPPS) to incorporate L-valine residues into peptide chains. The Fmoc protecting group allows for selective deprotection under mild basic conditions, facilitating sequential amino acid coupling.
Chemical Biology Research
As a protected amino acid, Fmoc-Val-OH is employed in the synthesis of peptides for biochemical research, protein structure studies, and the development of peptide-based therapeutics and diagnostics.
Organic Synthesis
This compound serves as a valuable chiral building block in various organic synthesis strategies where the introduction of a protected L-valine moiety is required.
| Molecular weight | 339.39 |
|---|---|
| Empirical formula | C20H21NO4 |
| Assay | ≥98.0% (HPLC) |
| Optical activity | [α]20/D −17±1°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Melting point | 143-145 °C(lit.)143-147 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Val-OH used for?
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Fmoc-Val-OH is primarily used as a building block in solid-phase peptide synthesis (SPPS) and other organic synthesis applications requiring the incorporation of a protected L-valine residue.
What are the CAS number and formula for Fmoc-Val-OH?
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The CAS number for Fmoc-Val-OH is 68858-20-8, and its empirical formula is C20H21NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Val-OH with an assay of ≥98.0% (HPLC). This product is not represented as USP, BP, or EP grade.
How should Fmoc-Val-OH be handled and stored?
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Fmoc-Val-OH should be handled with appropriate personal protective equipment, including eyeshields and gloves. It is recommended to store the compound at 2-8°C.
How are Tech Serve Solutions products packed and shipped?
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Tech Serve Solutions expertly packs and ships fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to stringent quality and safety standards.
How can I request a quote or sample for Fmoc-Val-OH?
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To request a quote or sample for Fmoc-Val-OH, please contact our sales team via the website or direct inquiry.
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