Fmoc-Tyr(tBu)-OPfp
Fmoc-Tyr(tBu)-OPfp (CAS 86060-93-7) is a fluorinated tyrosine derivative with the empirical formula C34H28F5NO5 and a molecular weight of 625.58. This compound serves as a valuable building block in peptide synthesis, particularly for introducing protected tyrosine residues. It is employed in chemical biology and organic synthesis for the development of complex peptides and modified biomolecules.
- IUPAC
- Fmoc-O-tert-butyl-L-tyrosine pentafluorophenyl ester
- Synonyms
- Fmoc-O-tert-butyl-L-tyrosine pentafluorophenyl ester

Peptide Synthesis
Utilised as a key reagent in solid-phase and solution-phase peptide synthesis for the incorporation of tert-butyl protected tyrosine residues. The Fmoc protecting group facilitates orthogonal deprotection strategies.
Chemical Biology Research
Applied in the construction of peptides for studying protein structure-function relationships, enzyme mechanisms, and signalling pathways. Its specific structure allows for the creation of modified peptides with tailored properties.
Organic Synthesis
Serves as an intermediate in the synthesis of various organic compounds where a protected tyrosine moiety is required. The pentafluorophenyl ester offers good reactivity for amide bond formation.
| Molecular weight | 625.58 |
|---|---|
| Empirical formula | C34H28F5NO5 |
| Assay | ≥96.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Tyr(tBu)-OPfp primarily used for?
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Fmoc-Tyr(tBu)-OPfp is primarily used as a protected amino acid derivative in peptide synthesis and for applications in chemical biology and organic synthesis.
What are the CAS number and empirical formula for Fmoc-Tyr(tBu)-OPfp?
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The CAS number is 86060-93-7 and the empirical formula is C34H28F5NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Tyr(tBu)-OPfp with an assay of ≥96.0% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should Fmoc-Tyr(tBu)-OPfp be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter such as type N95 (US) or type P1 (EN143) is recommended. Store at 2-8°C.
Is Fmoc-Tyr(tBu)-OPfp a controlled substance?
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The provided data does not indicate that Fmoc-Tyr(tBu)-OPfp is a controlled substance.
How are your chemicals packed and shipped?
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Fmoc-Tyr(tBu)-OPfp is carefully packed to ensure stability and safety during transit. We are a specialist global supplier and exporter, adhering to all necessary regulations for international shipments.
How can I request a sample or quote for Fmoc-Tyr(tBu)-OPfp?
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To request a sample or obtain a quote, please contact our sales department through the website or by phone, referencing the product name and CAS number 86060-93-7.
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