4-Chloromethyl-2,2-dimethyl-1,3-dioxolane
4-Chloromethyl-2,2-dimethyl-1,3-dioxolane (CAS: 4362-40-7) is a versatile organic building block with the molecular formula C6H11ClO2 and a molecular weight of 150.60 g/mol. This compound functions as a protected alcohol, featuring a chloromethyl group that enables diverse synthetic transformations. Its applications are primarily found in chemical synthesis, particularly for the introduction of protected hydroxymethyl moieties in complex organic molecules.
- Synonyms
- 4362-40-7C6H11ClO2

Organic Synthesis Intermediate
Serves as a key intermediate in the synthesis of more complex organic molecules. The dioxolane ring protects the diol functionality, while the chloromethyl group allows for nucleophilic substitution reactions.
Pharmaceutical Research
Used in the development of novel pharmaceutical compounds where precise control over functional groups is essential. Its structure allows for targeted modifications in drug discovery processes.
Agrochemical Development
Contributes to the synthesis of new agrochemicals, enabling the creation of compounds with specific biological activities for crop protection.
Material Science
Can be employed in the synthesis of specialized polymers or materials, introducing functionalized side chains or modifying polymer backbones.
| Molecular weight | 150.60 |
|---|---|
| Empirical formula | C6H11ClO2 |
| Assay | 97% |
| Boiling point | 156-158 °C(lit.) |
| Density | 1.063 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.434(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 53 °C / 127.4 °F |
| Transport (UN / ADR) | UN 1992 3/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 10-25 |
| Safety statements (S) | 16-23-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloromethyl-2,2-dimethyl-1,3-dioxolane used for?
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4-Chloromethyl-2,2-dimethyl-1,3-dioxolane is primarily used as a building block in organic synthesis, particularly for introducing protected hydroxymethyl groups into molecules. It finds applications in pharmaceutical research, agrochemical development, and material science.
What are the CAS number and formula for 4-Chloromethyl-2,2-dimethyl-1,3-dioxolane?
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The CAS number is 4362-40-7, and its empirical formula is C6H11ClO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chloromethyl-2,2-dimethyl-1,3-dioxolane with an assay of 97%. We do not represent this product as meeting USP, BP, EP, or other pharmacopoeial standards.
How should 4-Chloromethyl-2,2-dimethyl-1,3-dioxolane be handled safely?
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This compound is classified as Danger, with hazards including flammability (H226) and acute toxicity if swallowed (H301). Appropriate personal protective equipment, such as eyeshields, gloves, and respiratory protection (e.g., ABEK filter, full-face respirator), must be used. Handle in a well-ventilated area, away from ignition sources.
Is 4-Chloromethyl-2,2-dimethyl-1,3-dioxolane a controlled substance?
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The provided data does not indicate that 4-Chloromethyl-2,2-dimethyl-1,3-dioxolane is a controlled substance.
How is this chemical typically packaged and exported?
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Tech Serve Solutions, as a global supplier, packages and exports chemicals in compliance with international regulations for hazardous materials, including UN 1992 classification. Packaging options are available to suit various customer needs for research and industrial quantities.
How can I request a quote or sample?
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To request a quote or sample of 4-Chloromethyl-2,2-dimethyl-1,3-dioxolane, please visit the Tech Serve Solutions website and use our online inquiry form or contact our sales team directly.
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