4-tert-Butylphenylboronic acid

CAS 123324-71-0(CH3)3CC6H4B(OH)2Chemical Synthesis

Tech Serve Solutions is pleased to supply 4-tert-Butylphenylboronic acid (CAS: 123324-71-0), a valuable aryl boronic acid derivative with the linear formula (CH₃)₃CC₆H₄B(OH)₂ and a molecular weight of 178.04 g/mol. This compound serves as a critical building block in organic synthesis, particularly noted for its application in the preparation of tetracycline derivatives through cross-coupling reactions. It is supplied with an assay of ≥95.0%.

IUPAC: (p-tert-Butylphenyl)boronic acid,4-t-Butylbenzeneboronic acid,4-t-Butylphenylboronic acid,4-tert-Butylbenzeneboronic acid,p-tert-Butylbenzeneboronic acid,[4-(1,1-Dimethylethyl)phenyl]boronic acid
Synonyms: (p-tert-Butylphenyl)boronic acid4-t-Butylbenzeneboronic acid4-t-Butylphenylboronic acid4-tert-Butylbenzeneboronic acidp-tert-Butylbenzeneboronic acid[4-(1,1-Dimethylethyl)phenyl]boronic acid

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4-tert-Butylphenylboronic acid ((CH3)3CC6H4B(OH)2) — chemical structure, CAS 123324-71-0; Chemistry, fine chemical supplied by Tech Serve Solutions

Aryl Boronic AcidsBoronic AcidsChemical Synthesis

01 /Applications

Synthesis of Tetracycline Derivatives

4-tert-Butylphenylboronic acid is a key intermediate in the synthesis of complex molecules, including tetracycline derivatives. Its utility in cross-coupling reactions makes it indispensable for constructing specific carbon-carbon bonds in advanced pharmaceutical research.

Organic Synthesis Building Block

As an aryl boronic acid, this compound is a versatile reagent in general organic synthesis. It participates effectively in various palladium-catalyzed cross-coupling reactions, enabling the formation of new C-C and C-heteroatom bonds.

Research and Development

Primarily utilised in research and development settings, 4-tert-Butylphenylboronic acid facilitates the exploration of novel chemical structures and synthetic pathways. Its availability supports innovation in medicinal chemistry and materials science.

02 /Properties

Molecular weight	178.04
Linear formula	(CH3)3CC6H4B(OH)2
Assay	≥95.0%
Application	Cross-coupling building block used in synthesis of tetracycline derivatives.1
Melting point	191-196 °C(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

123324-71-0

MDL number

MFCD01009697

PubChem substance

24871543

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-tert-Butylphenylboronic acid used for?

4-tert-Butylphenylboronic acid is primarily used as a cross-coupling building block in the synthesis of tetracycline derivatives and for general organic synthesis research.

What is the CAS number and chemical formula for 4-tert-Butylphenylboronic acid?

The CAS number is 123324-71-0 and the linear chemical formula is (CH₃)₃CC₆H₄B(OH)₂.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 4-tert-Butylphenylboronic acid with an assay of ≥95.0%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should 4-tert-Butylphenylboronic acid be handled?

When handling 4-tert-Butylphenylboronic acid, it is essential to wear eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. Refer to the Safety Data Sheet for comprehensive handling information.

Is 4-tert-Butylphenylboronic acid a controlled substance?

The provided data does not indicate that 4-tert-Butylphenylboronic acid is a controlled substance.

How is 4-tert-Butylphenylboronic acid packed and exported?

Tech Serve Solutions packs and exports chemicals according to international shipping regulations to ensure safe and compliant delivery globally.

How can I request a sample or quote for 4-tert-Butylphenylboronic acid?

To request a sample or quote, please contact the TSS sales team through our website or by calling our office. Provide the product name and CAS number for prompt service.