4-tert-Butylphenylmagnesium bromide solution
4-tert-Butylphenylmagnesium bromide solution (CAS 63488-10-8) is a highly reactive organometallic compound, commonly supplied as a 2.0 M solution in diethyl ether. This Grignard reagent, with a molecular weight of 237.42 g/mol, is a valuable tool in organic synthesis. It is primarily utilised for introducing the 4-tert-butylphenyl group into various organic molecules, facilitating complex carbon-carbon bond formation in research and industrial applications.
Organic Synthesis Intermediate
As a Grignard reagent, it is extensively used in nucleophilic addition reactions to carbonyl compounds and other electrophiles. This allows for the synthesis of a wide array of complex organic molecules and intermediates.
Introduction of Aryl Groups
This reagent facilitates the efficient introduction of the 4-tert-butylphenyl moiety into diverse organic structures. This functionality is important in the synthesis of pharmaceuticals, agrochemicals, and advanced materials.
Research and Development
Utilised in academic and industrial research laboratories for exploring new synthetic pathways and developing novel chemical entities. Its reactivity profile makes it a versatile building block.
| Molecular weight | 237.42 |
|---|---|
| Linear formula | (CH3)3CC6H4MgBr |
| Density | 1.065 g/mL at 25 °C |
| Concentration | 2.0 M in diethyl ether |
Hazard statements
- H225Highly flammable liquid and vapour
- H250Catches fire spontaneously if exposed to air
- H261In contact with water releases flammable gas
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H336May cause drowsiness or dizziness
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P222Do not allow contact with air
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P422
| Flash point | -40 °C / -40 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-22-66-67 |
| Safety statements (S) | 16 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-tert-Butylphenylmagnesium bromide solution used for?
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4-tert-Butylphenylmagnesium bromide solution is primarily used as a Grignard reagent in organic synthesis to introduce the 4-tert-butylphenyl group into organic molecules, facilitating carbon-carbon bond formation.
What are the CAS number and formula for 4-tert-Butylphenylmagnesium bromide solution?
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The CAS number is 63488-10-8 and the linear formula is (CH3)3CC6H4MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 2.0 M solution in diethyl ether. We do not claim USP, BP, or EP grade as this is a reagent for chemical synthesis. It should be handled with appropriate laboratory precautions.
What are the safety and handling considerations for this product?
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This product is highly flammable (H225), pyrophoric (H250), and reacts violently with water (H261, supplemental hazard statement). It can cause severe skin burns and eye damage (H314) and may cause respiratory irritation (H336). It may also form explosive peroxides. Handle under an inert atmosphere, away from ignition sources and water. Appropriate personal protective equipment is essential.
How is 4-tert-Butylphenylmagnesium bromide solution shipped and exported?
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This chemical is shipped and exported according to international regulations for hazardous materials, identified as UN 2924, Class 8(3), Packing Group I. TSS ensures compliance with all relevant transport requirements.
How can I request a sample or quote?
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To request a sample or a quote, please use the contact form on our website or contact our sales department directly with your inquiry.
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