Fmoc-Tyr(PO3H2)-OH

CAS 147762-53-6C24H22NO8PChemical Synthesis

Nα-Fmoc-O-phospho-L-tyrosine (CAS: 147762-53-6) is a key phosphotyrosine derivative with the molecular formula C24H22NO8P and a molecular weight of 483.41. This compound serves as a crucial building block in peptide synthesis, particularly for creating phosphorylated peptides. Its applications span chemical biology and synthesis, enabling researchers to study protein phosphorylation events and develop novel peptidomimetics and therapeutic agents.

IUPAC: Nα-Fmoc-O-phospho-L-tyrosine
Synonyms: Nα-Fmoc-O-phospho-L-tyrosine

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Fmoc-Tyr(PO3H2)-OH (C24H22NO8P) — chemical structure, CAS 147762-53-6; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesChemical BiologyChemical SynthesisPeptide ChemistryTyrosine

01 /Applications

Peptide Synthesis

Utilised as a phosphotyrosine building block for the solid-phase or solution-phase synthesis of phosphorylated peptides. Essential for creating analogues of naturally occurring phosphopeptides involved in cellular signalling pathways.

Chemical Biology Research

Enables the investigation of protein-protein interactions mediated by phosphotyrosine residues. Useful in studying kinase and phosphatase activity and their roles in biological systems.

Drug Discovery

Serves as a scaffold or intermediate in the design and synthesis of novel pharmaceutical agents targeting phosphotyrosine-dependent signalling pathways implicated in diseases like cancer.

Biochemical Assays

Incorporated into peptides used in enzyme assays to study the specificity and kinetics of enzymes involved in phosphorylation and dephosphorylation.

02 /Properties

Molecular weight	483.41
Empirical formula	C24H22NO8P
Assay	≥95.0% (HPLC)
Storage temperature	−20°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

147762-53-6

MDL number

MFCD00235902

Beilstein registry

6674324

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-Tyr(PO3H2)-OH used for?

Fmoc-Tyr(PO3H2)-OH is primarily used as a protected phosphotyrosine building block in peptide synthesis for research in chemical biology, drug discovery, and biochemical assays, particularly for studying phosphorylation-dependent biological processes.

What is the CAS number and formula for Fmoc-Tyr(PO3H2)-OH?

The CAS number for Fmoc-Tyr(PO3H2)-OH is 147762-53-6, and its empirical formula is C24H22NO8P.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Fmoc-Tyr(PO3H2)-OH with an assay of ≥95.0% (HPLC). TSS does not represent this product as USP, BP, or EP grade.

What are the safety considerations when handling Fmoc-Tyr(PO3H2)-OH?

Handling Fmoc-Tyr(PO3H2)-OH requires appropriate personal protective equipment, including eyeshields and gloves. A respirator filter such as type N95 (US) or type P1 (EN143) is recommended. The substance is classified with WGK Germany 3, indicating a high hazard to water.

How is Fmoc-Tyr(PO3H2)-OH stored and shipped?

Fmoc-Tyr(PO3H2)-OH should be stored at -20°C. Tech Serve Solutions exports fine chemicals globally, adhering to all necessary shipping regulations.

How can I request a quote or sample for Fmoc-Tyr(PO3H2)-OH?

To request a quote or sample of Fmoc-Tyr(PO3H2)-OH, please contact our sales department through the website or by phone, providing the product name and CAS number.