Fmoc-Trp-OH
Fmoc-Trp-OH (CAS 35737-15-6), a protected form of L-tryptophan with the molecular formula C26H22N2O4, is a key building block in peptide synthesis. Its N-terminal Fmoc group facilitates controlled chain elongation in solid-phase and solution-phase peptide chemistry. This derivative is essential for incorporating tryptophan residues into peptides and proteins, supporting research in chemical biology and drug discovery.
- IUPAC
- Fmoc-L-tryptophan
Peptide Synthesis
Used as a protected amino acid for the incorporation of tryptophan into peptide chains during solid-phase or solution-phase synthesis. The Fmoc protecting group allows for sequential deprotection and coupling reactions.
Chemical Biology Research
Enables the study of peptides and proteins containing tryptophan, a biologically significant amino acid involved in protein structure and function. It aids in creating modified peptides for biological assays.
Drug Discovery and Development
Serves as an intermediate in the synthesis of potential therapeutic peptides or small molecules that mimic biological peptide interactions, contributing to pharmaceutical research.
Organic Synthesis
A versatile reagent in organic synthesis for constructing complex molecules that require a tryptophan moiety, leveraged in the development of novel chemical entities.
| Molecular weight | 426.46 |
|---|---|
| Empirical formula | C26H22N2O4 |
| Assay | ≥97.0% (HPLC) |
| Optical activity | [α]20/D −29±1°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Melting point | 182-185 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Trp-OH used for?
+
Fmoc-Trp-OH is primarily used as a protected amino acid in peptide synthesis, enabling the controlled incorporation of tryptophan residues into peptide chains for research in chemical biology, drug discovery, and organic synthesis.
What are the CAS number and molecular formula for Fmoc-Trp-OH?
+
The CAS number for Fmoc-Trp-OH is 35737-15-6, and its molecular formula is C26H22N2O4.
What grade and purity does Tech Serve Solutions supply for Fmoc-Trp-OH?
+
Tech Serve Solutions supplies Fmoc-Trp-OH with a purity of ≥97.0% (HPLC). This product is suitable for research and chemical synthesis purposes; TSS does not represent it as USP, BP, EP, or any other pharmacopoeial grade.
How should Fmoc-Trp-OH be handled and stored?
+
Fmoc-Trp-OH should be handled with appropriate personal protective equipment, including eyeshields and gloves. It requires refrigeration and should be stored at 2-8°C to maintain its integrity.
Is Fmoc-Trp-OH subject to any special regulations?
+
Based on the provided data, there is no indication of Fmoc-Trp-OH being a controlled or scheduled substance. Standard laboratory safety protocols should be followed.
How can I request a sample or quote for Fmoc-Trp-OH?
+
To request a sample or a quote for Fmoc-Trp-OH, please contact the Tech Serve Solutions sales team through our website or by calling our dedicated sales line.
How is Fmoc-Trp-OH typically packed and exported?
+
Fmoc-Trp-OH is supplied in appropriate packaging suitable for chemical reagents and is available for global export by Tech Serve Solutions, adhering to international shipping regulations for fine chemicals.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis