4-(Trifluoromethyl)mandelic acid
4-(Trifluoromethyl)mandelic acid (CAS: 395-35-7), with the molecular formula CF3C6H4CH(OH)CO2H and a molecular weight of 220.15 g/mol, is a valuable organic compound. It functions as a key building block in organic synthesis, particularly useful in the preparation of more complex molecules. Its structure, featuring both a carboxylic acid and a hydroxyl group along with a trifluoromethylphenyl moiety, lends itself to diverse chemical transformations.

Organic Synthesis Intermediate
Utilised as a versatile intermediate in the synthesis of fine chemicals and pharmaceutical building blocks. The trifluoromethyl group offers unique electronic properties for target molecules.
Research and Development
Employed in academic and industrial research settings for the development of novel compounds and materials. Its reactivity allows for incorporation into various synthetic pathways.
Chiral Synthesis
Serves as a precursor in chiral synthesis, where its stereogenic centre can be exploited to create enantiomerically pure compounds.
| Molecular weight | 220.15 |
|---|---|
| Linear formula | CF3C6H4CH(OH)CO2H |
| Assay | 98% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethyl)mandelic acid used for?
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4-(Trifluoromethyl)mandelic acid is primarily used as a building block and intermediate in organic synthesis, particularly in the development of fine chemicals and pharmaceuticals, and in research and development settings.
What is the CAS number and chemical formula for 4-(Trifluoromethyl)mandelic acid?
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The CAS number is 395-35-7 and the chemical formula is CF3C6H4CH(OH)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Trifluoromethyl)mandelic acid with an assay of 98%. This product is intended for research and industrial use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should 4-(Trifluoromethyl)mandelic acid be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use a type N95 (US) or P1 (EN143) respirator filter if necessary. It is classified with WGK Germany 3.
Does TSS export 4-(Trifluoromethyl)mandelic acid?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-(Trifluoromethyl)mandelic acid.
How can I request a quote or sample for 4-(Trifluoromethyl)mandelic acid?
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Please contact our sales team through the website or by phone to request a quote or sample for 4-(Trifluoromethyl)mandelic acid.
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