4-(Trifluoromethyl)hydrocinnamic acid
4-(Trifluoromethyl)hydrocinnamic acid (CAS: 53473-36-2), with the molecular formula CF3C6H4CH2CH2CO2H and a molecular weight of 218.17 g/mol, is a valuable organic building block. This carboxylic acid derivative is primarily utilised in chemical synthesis and as a key intermediate in the development of more complex organic molecules for research and industrial applications. Its structure, featuring a trifluoromethyl group and a propionic acid chain, lends itself to diverse synthetic strategies.
- IUPAC
- 3-[4-(Trifluoromethyl)phenyl]propionic acid
- Synonyms
- 3-[4-(Trifluoromethyl)phenyl]propionic acid
Organic Synthesis Intermediate
Serves as a crucial building block in multi-step organic synthesis pathways. Its carboxylic acid functionality and trifluoromethylphenyl moiety enable diverse chemical transformations.
Pharmaceutical Research
Utilised in the exploratory synthesis of potential pharmaceutical agents and drug candidates. The trifluoromethyl group can modulate lipophilicity and metabolic stability in target molecules.
Material Science Precursor
Can be employed as a precursor in the development of novel materials where specific electronic or physical properties are desired, influenced by the fluorinated aromatic ring.
Agrochemical Development
Investigated for its potential use in the synthesis of new agrochemical compounds, leveraging its unique structural features for biological activity.
| Molecular weight | 218.17 |
|---|---|
| Linear formula | CF3C6H4CH2CH2CO2H |
| Assay | 95% |
| Melting point | 106-110 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethyl)hydrocinnamic acid used for?
+
4-(Trifluoromethyl)hydrocinnamic acid is primarily used as a building block in organic synthesis and as an intermediate in pharmaceutical and agrochemical research and development.
What are the CAS number and chemical formula for 4-(Trifluoromethyl)hydrocinnamic acid?
+
The CAS number is 53473-36-2 and the chemical formula is CF3C6H4CH2CH2CO2H.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 4-(Trifluoromethyl)hydrocinnamic acid with an assay of 95%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 4-(Trifluoromethyl)hydrocinnamic acid be handled safely?
+
Handle with appropriate personal protective equipment, including a dust mask (type N95 recommended), eyeshields, and gloves. Avoid breathing dust/fume/gas/mist/vapours/spray. In case of contact with eyes, rinse cautiously with water for several minutes. Ensure good ventilation.
Is 4-(Trifluoromethyl)hydrocinnamic acid a controlled substance?
+
The provided data does not indicate that 4-(Trifluoromethyl)hydrocinnamic acid is a controlled substance.
How is 4-(Trifluoromethyl)hydrocinnamic acid packed and shipped?
+
This chemical is typically packed in quantities suitable for laboratory and industrial use, adhering to all relevant shipping regulations for hazardous materials. TSS exports globally.
How can I request a quote or sample of 4-(Trifluoromethyl)hydrocinnamic acid?
+
Please contact our sales department via the website or direct email to request a quotation or a sample of 4-(Trifluoromethyl)hydrocinnamic acid.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis