4-(Trifluoromethyl)benzylamine
4-(Trifluoromethyl)benzylamine (CAS: 3300-51-4) is an organic compound with the formula CF3C6H4CH2NH2. With a molecular weight of 175.15 g/mol, this amine serves as a valuable building block in organic synthesis. It is frequently employed in the development of novel chemical entities within pharmaceutical research and materials science, contributing to the creation of complex molecular architectures.
Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of various organic compounds. Its trifluoromethylbenzyl group offers unique electronic and steric properties for derivatisation.
Pharmaceutical Research
Applied in the construction of potential drug candidates. For example, it has been used in the synthesis of 3-[(2,4-dioxothiazolidin-5-yl)methyl]benzamide derivatives, which may have biological relevance.
Building Block for Complex Molecules
Serves as a versatile building block in academic and industrial research for creating more complex chemical structures and functionalised molecules.
| Molecular weight | 175.15 |
|---|---|
| Linear formula | CF3C6H4CH2NH2 |
| Assay | 97% |
| Density | 1.229 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.464(lit.) |
| Application | 4-(Trifluoromethyl)benzylamine has been used in the synthesis of 3-[(2,4-dioxothiazolidin-5-yl)methyl]benzamide derivatives1. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 75 °C / 167 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... AOC3(8639)mouse ... Aoc3(11754) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethyl)benzylamine used for?
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4-(Trifluoromethyl)benzylamine is primarily used as an intermediate in organic synthesis and in pharmaceutical research for building complex molecules, such as 3-[(2,4-dioxothiazolidin-5-yl)methyl]benzamide derivatives.
What are the CAS number and formula for 4-(Trifluoromethyl)benzylamine?
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The CAS number is 3300-51-4 and the chemical formula is CF3C6H4CH2NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Trifluoromethyl)benzylamine with an assay of 97%. This product is typically for research and development use and is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
How should 4-(Trifluoromethyl)benzylamine be handled safely?
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Handle with appropriate personal protective equipment including eyeshields, gloves, and a suitable respirator (e.g., type ABEK). Avoid breathing vapours or dust. Ensure adequate ventilation as it may cause skin, eye, and respiratory irritation (H315, H319, H335).
How is 4-(Trifluoromethyl)benzylamine packed, shipped, and exported?
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As a global supplier, Tech Serve Solutions ensures proper packaging and adheres to international shipping regulations for chemicals like 4-(Trifluoromethyl)benzylamine. It is shipped according to applicable transport codes such as NA 1993.
How can I request a sample or a quote for 4-(Trifluoromethyl)benzylamine?
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Please contact our sales team via the website or by phone to request a sample or a quotation for 4-(Trifluoromethyl)benzylamine. Specify the quantity and your intended application.
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