4-(Trifluoromethyl)benzoyl chloride
4-(Trifluoromethyl)benzoyl chloride (CAS 329-15-7) is an organic compound with the linear formula CF<sub>3</sub>C<sub>6</sub>H<sub>4</sub>COCl and a molecular weight of 208.56 g/mol. This acid halide is a versatile building block utilized in organic synthesis. Its reactive acyl chloride group readily participates in acylation reactions, making it valuable for introducing the 4-(trifluoromethyl)benzoyl moiety into various organic structures. It finds application in the synthesis of complex molecules and intermediates.
- IUPAC
- α,α,α-Trifluoro-p-toluoyl chloride
- Synonyms
- α,α,α-Trifluoro-p-toluoyl chloride
Organic Synthesis Intermediate
Serves as a crucial intermediate in the synthesis of diverse organic compounds, particularly pharmaceuticals and agrochemicals. The trifluoromethyl group offers unique electronic and lipophilic properties to the target molecules.
Acylation Agent
Employed as an efficient acylation agent due to the reactivity of the acyl chloride functional group. It is used to introduce the 4-(trifluoromethyl)benzoyl group into alcohols, amines, and other nucleophiles.
Building Block for Fluorinated Compounds
Acts as a key building block in the construction of fluorinated organic molecules. The presence of the CF<sub>3</sub> group is important for modulating the physicochemical and biological properties of the resulting compounds.
| Molecular weight | 208.56 |
|---|---|
| Linear formula | CF3C6H4COCl |
| Assay | 97% |
| Boiling point | 188-190 °C(lit.)78-79 °C/16 mmHg(lit.) |
| Density | 1.404 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.476(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 78 °C / 172.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethyl)benzoyl chloride used for?
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4-(Trifluoromethyl)benzoyl chloride is primarily used as an intermediate in organic synthesis and as an acylation agent for introducing the 4-(trifluoromethyl)benzoyl moiety into various organic structures, including pharmaceuticals and agrochemicals.
What is the CAS number and formula for 4-(Trifluoromethyl)benzoyl chloride?
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The CAS number for 4-(Trifluoromethyl)benzoyl chloride is 329-15-7, and its linear formula is CF<sub>3</sub>C<sub>6</sub>H<sub>4</sub>COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Trifluoromethyl)benzoyl chloride with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 4-(Trifluoromethyl)benzoyl chloride be handled safely?
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This compound is corrosive and causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including gloves, goggles, a face shield, and a suitable respirator. Ensure adequate ventilation.
Is 4-(Trifluoromethyl)benzoyl chloride available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-(Trifluoromethyl)benzoyl chloride, adhering to international shipping regulations.
How can I request a quote or sample?
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To request a quote or sample of 4-(Trifluoromethyl)benzoyl chloride, please use the contact form on our website or contact our sales department directly.
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