4-(Trifluoromethyl)benzhydrazide
4-(Trifluoromethyl)benzhydrazide (CAS 339-59-3) is a white to off-white crystalline solid with the linear formula CF₃C₆H₄CONHNH₂ and a molecular weight of 204.15 g/mol. This organic compound serves as a valuable building block in chemical synthesis, particularly within the pharmaceutical and agrochemical industries. Its structure, featuring a trifluoromethyl group and a hydrazide moiety, makes it a useful intermediate for creating more complex molecular architectures. TSS supplies this chemical with an assay of 97%.
- IUPAC
- α,α,α-Trifluoro-p-toluic acid hydrazide

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) where the trifluoromethylphenyl or hydrazide functional groups are required. It serves as a key building block for developing novel therapeutic agents.
Agrochemical Development
Applied as a precursor in the research and development of new pesticides, herbicides, and fungicides. The trifluoromethyl group can impart desirable properties such as enhanced stability and efficacy.
Organic Synthesis Reagent
A versatile reagent in organic chemistry laboratories for constructing diverse heterocyclic compounds and other complex organic molecules. Its reactivity allows for various derivatizations.
| Molecular weight | 204.15 |
|---|---|
| Linear formula | CF3C6H4CONHNH2 |
| Assay | 97% |
| Melting point | 115-119 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethyl)benzhydrazide used for?
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4-(Trifluoromethyl)benzhydrazide is primarily used as a building block and intermediate in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It is also employed in general chemical synthesis research.
What are the CAS number and chemical formula for 4-(Trifluoromethyl)benzhydrazide?
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The CAS number is 339-59-3, and the linear chemical formula is CF₃C₆H₄CONHNH₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Trifluoromethyl)benzhydrazide with an assay of 97%. This product is intended for laboratory and research use; TSS does not represent it as USP, BP, EP, or any other pharmacopoeial grade.
What are the main safety hazards associated with 4-(Trifluoromethyl)benzhydrazide?
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According to GHS classifications, 4-(Trifluoromethyl)benzhydrazide is a Warning substance. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used when handling.
How is 4-(Trifluoromethyl)benzhydrazide typically shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, handling the logistics for international shipment of products like 4-(Trifluoromethyl)benzhydrazide in compliance with all relevant regulations.
How can I request a sample or quote for 4-(Trifluoromethyl)benzhydrazide?
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To request a sample or a quote for 4-(Trifluoromethyl)benzhydrazide, please use the contact form on our website or reach out to our sales team directly. Please specify the quantity required.
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