4-(Trifluoromethyl)benzenesulfonyl chloride
Tech Serve Solutions proudly supplies 4-(Trifluoromethyl)benzenesulfonyl chloride (CAS: 2991-42-6; Formula: CF3C6H4SO2Cl; MW: 244.62). This organic compound serves as a vital building block in chemical synthesis. Its reactive sulfonyl chloride group makes it a key intermediate for introducing the 4-(trifluoromethyl)benzenesulfonyl moiety into various molecules, particularly in the development of pharmaceuticals and agrochemicals. Offered at 97% purity, it is suitable for research and industrial applications.

Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs) where the trifluoromethylbenzenesulfonyl group is a required structural element for biological activity.
Agrochemical Synthesis
Acts as a precursor for the development of novel herbicides, insecticides, and fungicides, leveraging its specific chemical reactivity.
Organic Building Block
Facilitates the introduction of the CF3C6H4SO2- functional group into complex organic molecules during multi-step syntheses.
Reagent in Organic Chemistry
Employed in laboratory settings for various sulfonylations and derivatization reactions, contributing to chemical research.
| Molecular weight | 244.62 |
|---|---|
| Linear formula | CF3C6H4SO2Cl |
| Assay | 97% |
| Melting point | 30-34 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-34 |
| Safety statements (S) | 22-26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethyl)benzenesulfonyl chloride used for?
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4-(Trifluoromethyl)benzenesulfonyl chloride is primarily used as a building block in organic synthesis, particularly for the preparation of pharmaceuticals and agrochemicals, and as a reagent in chemical research.
What are the CAS number and formula for this compound?
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The CAS number is 2991-42-6 and the linear formula is CF3C6H4SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Trifluoromethyl)benzenesulfonyl chloride with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for 4-(Trifluoromethyl)benzenesulfonyl chloride?
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This compound is classified as Danger and causes severe skin burns and eye damage (H314). It also reacts violently with water. Appropriate personal protective equipment, including gloves, goggles, and face shields, must be worn. Handle in a well-ventilated area and avoid contact with water.
How is 4-(Trifluoromethyl)benzenesulfonyl chloride packed and shipped?
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Tech Serve Solutions adheres to strict international regulations for packing and shipping chemicals, including hazardous materials like 4-(Trifluoromethyl)benzenesulfonyl chloride (UN 3261, Class 8, PG II), ensuring safe export globally.
How can I request a quote or sample?
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To request a quote or a sample of 4-(Trifluoromethyl)benzenesulfonyl chloride, please contact our sales department through the website or by phone, providing your specific requirements.
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