FTI-276 trifluoroacetate salt
FTI-276 trifluoroacetate salt (CAS: 170006-72-1 free base) is a bioactive small molecule with the empirical formula C21H27N3O3S2 ·C2HF3O2 and a molecular weight of 547.61. This off-white film is primarily utilised in biochemical research, particularly within cell biology and neuroscience studies. It functions as an enzyme inhibitor, specifically targeting farnesyl transferase, and plays a role in understanding G protein function and post-translational modifications. TSS supplies this compound for research purposes.
- IUPAC
- N-[4-[2-(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine trifluoroacetate salt
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Enzyme Inhibition Studies
FTI-276 trifluoroacetate salt serves as a potent inhibitor of farnesyl transferase, a key enzyme involved in protein prenylation. This makes it valuable for research into cellular processes regulated by prenylation.
Cell Biology Research
As a bioactive small molecule, it is employed in cell biology to investigate cellular signaling pathways and mechanisms, including those related to G protein function.
Neuroscience Investigations
This compound is utilised in neuroscience research to explore the role of farnesyl transferase and related signaling in neuronal function and development.
Post-translational Modification Studies
FTI-276 trifluoroacetate salt aids in the study of post-translational modifications, offering a tool to investigate the impact of farnesyl transferase inhibition on protein function.
| Molecular weight | 547.61 |
|---|---|
| Empirical formula | C21H27N3O3S2 ·C2HF3O2 |
| Assay | ≥95% (HPLC) |
| Form | film |
| Colour | off-white |
| Solubility | H2O: >5 mg/mL |
| Storage temperature | −20°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | wet ice |
|---|---|
| Storage Condition | desiccatedunder inert gas |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is FTI-276 trifluoroacetate salt primarily used for?
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FTI-276 trifluoroacetate salt is primarily used for research purposes, particularly in studies involving enzyme inhibition (farnesyl transferase), cell biology, neuroscience, and post-translational modifications.
What are the CAS number and molecular formula for FTI-276 trifluoroacetate salt?
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The CAS number for the free base is 170006-72-1. The empirical formula for the trifluoroacetate salt is C21H27N3O3S2 ·C2HF3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies FTI-276 trifluoroacetate salt with an assay of ≥95% (HPLC). This compound is supplied for research purposes and TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling recommendations for FTI-276 trifluoroacetate salt?
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FTI-276 trifluoroacetate salt is classified with GHS07 and a 'Warning' signal word, with hazard statements H315, H319, and H335 indicating it causes skin irritation, serious eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area and avoid breathing dust.
How is FTI-276 trifluoroacetate salt shipped and stored?
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This product is shipped in wet ice and should be stored desiccated under inert gas at -20°C.
How can I request a quote or sample for FTI-276 trifluoroacetate salt?
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To request a quote or sample, please contact the Tech Serve Solutions sales team through our website or by telephone.
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