4-(Trifluoromethyl)benzylsulfonyl chloride

CAS 163295-75-8C8H6ClF3O2SChemical Synthesis

4-(Trifluoromethyl)benzylsulfonyl chloride (CAS: 163295-75-8; Formula: C8H6ClF3O2S; Molar Mass: 258.65) is a versatile organic building block and a sulfonyl halide. Characterised by its trifluoromethyl and sulfonyl chloride functionalities, it serves as a key intermediate in the synthesis of more complex molecules. Its reactivity makes it valuable in various chemical synthesis applications, particularly for introducing the 4-(trifluoromethyl)benzylsulfonyl moiety into organic structures.

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4-(Trifluoromethyl)benzylsulfonyl chloride (C8H6ClF3O2S) — chemical structure, CAS 163295-75-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksChemical SynthesisOrganic Building BlocksSulfonyl HalidesSulfur Compounds

01 /Applications

Organic Synthesis Intermediate

This compound acts as a crucial building block in organic synthesis, enabling the formation of new carbon-sulfur bonds. It is used to introduce the 4-(trifluoromethyl)benzylsulfonyl group into target molecules.

Pharmaceutical Research

As a functionalized intermediate, it is employed in the development of novel pharmaceutical compounds. The trifluoromethyl group can influence pharmacokinetic properties, making it attractive for drug discovery.

Agrochemical Development

The unique structural features of 4-(trifluoromethyl)benzylsulfonyl chloride make it a potential precursor for the synthesis of new agrochemicals. It can be incorporated into molecules designed for crop protection.

02 /Properties

Molecular weight	258.65
Empirical formula	C8H6ClF3O2S
Assay	97%
Melting point	103-107 °C

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Danger

Hazard statements

H302Harmful if swallowed
H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 3261 8 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	22-34
Safety statements (S)	26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

163295-75-8

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-(Trifluoromethyl)benzylsulfonyl chloride used for?

4-(Trifluoromethyl)benzylsulfonyl chloride is primarily used as a building block and intermediate in organic synthesis, particularly in pharmaceutical and agrochemical research, to introduce the 4-(trifluoromethyl)benzylsulfonyl moiety.

What is the CAS number and chemical formula for 4-(Trifluoromethyl)benzylsulfonyl chloride?

The CAS number is 163295-75-8 and the chemical formula is C8H6ClF3O2S.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 4-(Trifluoromethyl)benzylsulfonyl chloride with an assay of 97%. We do not represent this product as USP, BP, or EP grade.

How should 4-(Trifluoromethyl)benzylsulfonyl chloride be handled safely?

Handling requires caution due to its corrosive and harmful nature. Users must wear appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection. Refer to the safety data sheet for full details on hazard statements (H302-H314) and precautionary measures.

Is 4-(Trifluoromethyl)benzylsulfonyl chloride available for export?

Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-(Trifluoromethyl)benzylsulfonyl chloride. Please contact us for export details.

How can I request a quote or sample?

To request a quote or sample of 4-(Trifluoromethyl)benzylsulfonyl chloride, please use the 'Request a Quote' or 'Request a Sample' buttons on our product page, or contact our sales team directly.