5-Fluoro-1-indanone
5-Fluoro-1-indanone (CAS: 700-84-5; Formula: C9H7FO; MW: 150.15) is a fluorinated ketone and a valuable building block in organic synthesis. This compound serves as a precursor in the preparation of thiosemicarbazones derived from 1-indanones and has been utilised in the synthesis of certain heterocyclic compounds like 6-fluoro-1,2,3,4-tetrahydroquinoline hydrochloride. Tech Serve Solutions offers this chemical with a high purity assay.
Synthesis of Thiosemicarbazones
5-Fluoro-1-indanone is employed as a starting material in the synthesis of thiosemicarbazones that are derived from the 1-indanone structural motif.
Preparation of Fluorinated Heterocycles
This compound has been used in the preparation of 6-fluoro-1,2,3,4-tetrahydroquinoline hydrochloride, demonstrating its utility in constructing fluorinated heterocyclic systems.
Organic Synthesis Building Block
As a fluorinated ketone, 5-Fluoro-1-indanone serves as a versatile building block for introducing fluorine atoms and indanone frameworks into more complex organic molecules.
| Molecular weight | 150.15 |
|---|---|
| Empirical formula | C9H7FO |
| Assay | 99% |
| Boiling point | 113-114 °C(lit.) |
| Density | 1.216 g/mL at 25 °C(lit.) |
| Application | 5-Fluoro-1-indanone was used to prepare precursor for thiosemicarbazones derived from 1-indanones1. It was used in the synthesis of 6-fluoro-1,2,3,4-tetrahydroquinoline hydrochloride2. |
| Melting point | 38-40 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Fluoro-1-indanone used for?
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5-Fluoro-1-indanone is primarily used as a building block in organic synthesis, including the preparation of thiosemicarbazones and fluorinated heterocyclic compounds.
What is the CAS number and formula for 5-Fluoro-1-indanone?
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The CAS number is 700-84-5 and the empirical formula is C9H7FO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Fluoro-1-indanone with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should 5-Fluoro-1-indanone be handled safely?
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5-Fluoro-1-indanone is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and eye irritation. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (N95), in a well-ventilated area. Refer to the Safety Data Sheet for full details.
Is 5-Fluoro-1-indanone a controlled substance?
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The provided data does not indicate that 5-Fluoro-1-indanone is a controlled substance.
How is 5-Fluoro-1-indanone shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and can arrange appropriate packaging and shipping for international export. Please contact us for details.
How can I request a sample or quote for 5-Fluoro-1-indanone?
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To request a sample or a quotation for 5-Fluoro-1-indanone, please use the contact form on our website or contact our sales department directly.
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