5-Ethynyl-2′-deoxyuridine, (EdU)
5-Ethynyl-2′-deoxyuridine (EdU), CAS 61135-33-9, with a molecular weight of 252.22 g/mol, is a vital nucleoside analog. It serves as a powerful tool for investigating short-term DNA synthesis in biological systems where sustained cell viability is not paramount. EdU is instrumental in studies concerning cell proliferation, differentiation, nuclear architecture analysis, and tissue regeneration, offering precise insights into cellular processes.
- Synonyms
- 5-Ethynyl-2'-deoxyuridine5-Ethynyluridine 2'-deoxy-EdU(2R,3R,4S,5R)-5-(5-ethynylpyrimidin-2-yl)oxy-3,4-dihydro-2,5-bis(hydroxymethyl)oxan-2-ol
Cell Proliferation and Differentiation Studies
EdU is a key reagent for tracking and quantifying cell proliferation and differentiation. Its ability to incorporate into newly synthesised DNA allows researchers to visualise and measure these dynamic cellular processes with high fidelity.
Analysis of Nuclear Architecture
This nucleoside analog aids in understanding the organisation and dynamics of the cell nucleus. By labelling replicating DNA, EdU can provide insights into nuclear structure and function during different cellular states.
Tissue Regeneration Research
In studies focused on tissue repair and regeneration, EdU is used to monitor the rate and extent of cell division within regenerating tissues. This helps in evaluating the efficacy of regenerative strategies.
Probing DNA Synthesis
EdU is specifically designed to label cells undergoing DNA synthesis, making it ideal for short-term assessments of replication in various biological contexts, including tissue culture and in vivo models.
| Molecular weight | 252.22 |
|---|---|
| Empirical formula | C11H12N2O5 |
| Application | A powerful nucleoside analog for probing short-term DNA synthesis in tissue culture and living organisms where prolonged cell survival is not required.1 Suitable for a variety of applications such as cell proliferation and differentiation studies2,3, analysis of nuclear architecture,4 and tissue regeneration studies.5 |
Hazard statements
- H340May cause genetic defects
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P201Obtain special instructions before use
- P281Use personal protective equipment as required
- P308IF exposed or concerned
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | T |
| Risk statements (R) | 46-61 |
| Safety statements (S) | 53-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Ethynyl-2′-deoxyuridine (EdU) used for?
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5-Ethynyl-2′-deoxyuridine (EdU) is used as a powerful nucleoside analog for probing short-term DNA synthesis in tissue culture and living organisms. It is suitable for cell proliferation and differentiation studies, analysis of nuclear architecture, and tissue regeneration research.
What are the CAS number and molecular formula for EdU?
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The CAS number for 5-Ethynyl-2′-deoxyuridine (EdU) is 61135-33-9. Its molecular formula is C11H12N2O5.
What grade and purity does Tech Serve Solutions supply for EdU?
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Tech Serve Solutions supplies EdU typically as a research-grade chemical. Purity information is available on the product's Certificate of Analysis. We do not represent this product as USP, BP, EP, or pharmacopoeia grade unless explicitly stated.
How should EdU be handled safely?
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EdU is classified with GHS08 signal word 'Danger' and carries hazard statements H340 (May cause genetic defects) and H361 (Suspected of damaging fertility or the unborn child). Handle with extreme caution in a well-ventilated area, wearing appropriate personal protective equipment (P201, P281). If exposed or concerned, seek immediate medical attention (P308 + P313).
Is EdU available for international export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 5-Ethynyl-2′-deoxyuridine (EdU), and can facilitate international shipments.
How can I request a sample or quote for EdU?
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To request a sample or a quotation for 5-Ethynyl-2′-deoxyuridine (EdU), please contact our sales team through the website or by calling our main office. Please specify the quantity required.
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