5-Ethynyl-2′-deoxycytidine, (EdC)
5-Ethynyl-2'-deoxycytidine (CAS: 69075-47-4) is a deoxycytidine analogue featuring an ethynyl group. With a molecular weight of 251.24 g/mol and the empirical formula C11H13N3O4, this compound is primarily utilised in chemical biology for the metabolic labelling of newly synthesised DNA in vivo. It serves as a valuable alternative when thymidine analogue incorporation is undesirable, offering researchers a unique tool for molecular investigations.
- Synonyms
- C11H13N3O45-Ethynyl-2'-deoxycytidine

Metabolic DNA Labelling
5-Ethynyl-2'-deoxycytidine functions as a relatively non-toxic nucleoside analogue for labelling newly synthesised DNA within living systems. This method is particularly useful for tracking DNA synthesis and turnover in various biological contexts.
Chemical Biology Research
As an advanced research chemical, EdC facilitates studies in chemical biology, allowing for the incorporation of modified nucleosides into DNA. This enables sophisticated experiments related to DNA structure, function, and cellular processes.
Nucleoside Chemistry
This compound is a key reagent in nucleoside chemistry, contributing to the synthesis of modified nucleic acids and the development of novel therapeutic agents or diagnostic tools.
| Molecular weight | 251.24 |
|---|---|
| Empirical formula | C11H13N3O4 |
| Application | A relatively nontoxic 2’-deoxycytidine analog for metabolic labeling of newly synthesized DNA in vivo.1,2 Especially suitable if the use of thymidine analogs is undesirable. |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Ethynyl-2′-deoxycytidine used for?
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5-Ethynyl-2′-deoxycytidine is primarily used as a relatively non-toxic analogue for the metabolic labelling of newly synthesised DNA in vivo, especially when thymidine analogue use is undesirable.
What is the CAS number and formula for 5-Ethynyl-2′-deoxycytidine?
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The CAS number for 5-Ethynyl-2′-deoxycytidine is 69075-47-4, and its empirical formula is C11H13N3O4.
What grade and purity does Tech Serve Solutions supply for 5-Ethynyl-2′-deoxycytidine?
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Tech Serve Solutions supplies 5-Ethynyl-2′-deoxycytidine for research purposes. The specific grade and purity are available upon request; it is not supplied as USP, BP, or EP grade.
How should 5-Ethynyl-2′-deoxycytidine be handled?
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According to the WGK Germany classification, 5-Ethynyl-2′-deoxycytidine is a water-polluting substance. Handle with appropriate personal protective equipment in a well-ventilated area to avoid exposure and environmental contamination.
How is 5-Ethynyl-2′-deoxycytidine packed and shipped?
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Tech Serve Solutions offers global export services for 5-Ethynyl-2′-deoxycytidine, ensuring secure and compliant packaging and shipping to meet international standards for chemical supply.
How can I request a quote or sample for 5-Ethynyl-2′-deoxycytidine?
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To request a quote or a sample of 5-Ethynyl-2′-deoxycytidine, please contact the Tech Serve Solutions sales team through our website or by phone, providing your specific requirements.
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